Skeletal editing through direct nitrogen deletion of secondary amines
SH Kennedy, BD Dherange, KJ Berger, MD Levin - Nature, 2021 - nature.com
Synthetic chemistry aims to build up molecular complexity from simple feedstocks. However,
the ability to exert precise changes that manipulate the connectivity of the molecular …
the ability to exert precise changes that manipulate the connectivity of the molecular …
Anomeric amides—structure, properties and reactivity
SA Glover - Tetrahedron, 1998 - Elsevier
Amides, geminally substituted with two heteroatoms at nitrogen, can support anomeric
effects in much the same way as their carbon analogues such as acetals and aminals. To …
effects in much the same way as their carbon analogues such as acetals and aminals. To …
Pd(II)-Catalyzed Cross-Coupling of sp3 C−H Bonds with sp2 and sp3 Boronic Acids Using Air as the Oxidant
O-Methyl hydroxamic acids, readily available from carboxylic acids, are found to be
extremely reactive for β-C− H activation by Pd (OAc) 2. This reactivity is exploited to develop …
extremely reactive for β-C− H activation by Pd (OAc) 2. This reactivity is exploited to develop …
[图书][B] The Chemistry of Hydroxylamines, Oximes and Hydroxamic Acids, Volume 1
Z Rappoport, JF Liebman - 2008 - books.google.com
Page 1 Patai Series: The Chemistry of Functional Groups Series Editor: Zvi Rappoport Volume
Editors: Zvi Rappoport & Joel F. Liebman The Chemistry of Hyd roxylamines, Oximes and …
Editors: Zvi Rappoport & Joel F. Liebman The Chemistry of Hyd roxylamines, Oximes and …
Ambient and aerobic carbon–carbon bond cleavage toward α-ketoester synthesis by transition-metal-free photocatalysis
Q Yu, Y Zhang, JP Wan - Green Chemistry, 2019 - pubs.rsc.org
The α-oxoesterification of the CC double bond in readily available enaminones enabling
efficient synthesis of α-ketoesters is developed. The reactions showing general tolerance to …
efficient synthesis of α-ketoesters is developed. The reactions showing general tolerance to …
Ligand-enabled β-C–H arylation of α-amino acids using a simple and practical auxiliary
G Chen, T Shigenari, P Jain, Z Zhang… - Journal of the …, 2015 - ACS Publications
Pd-catalyzed β-C–H functionalizations of carboxylic acid derivatives using an auxiliary as a
directing group have been extensively explored in the past decade. In comparison to the …
directing group have been extensively explored in the past decade. In comparison to the …
[HTML][HTML] Heteroatom substitution at amide nitrogen—resonance reduction and HERON reactions of anomeric amides
This review describes how resonance in amides is greatly affected upon substitution at
nitrogen by two electronegative atoms. Nitrogen becomes strongly pyramidal and resonance …
nitrogen by two electronegative atoms. Nitrogen becomes strongly pyramidal and resonance …
Direct ester condensation from a 1: 1 mixture of carboxylic acids and alcohols catalyzed by hafnium (IV) or zirconium (IV) salts
K Ishihara, M Nakayama, S Ohara, H Yamamoto - Tetrahedron, 2002 - Elsevier
To promote atom efficiency in synthesis and to avoid the generation of environmental waste,
the use of stoichiometric amounts of condensing reagents or excess substrates should be …
the use of stoichiometric amounts of condensing reagents or excess substrates should be …
Transition-Metal-Assisted Radical/Radical Cross-Coupling: A New Strategy to the Oxidative C(sp3)–H/N–H Cross-Coupling
A transition-metal-assisted oxidative C (sp3)-H/N–H cross-coupling reaction of N-
alkoxyamides with aliphatic hydrocarbons is described. During the reaction, nitrogen …
alkoxyamides with aliphatic hydrocarbons is described. During the reaction, nitrogen …
Palladium-Catalyzed Alkoxylation of N-Methoxybenzamides via Direct sp2 C−H Bond Activation
GW Wang, TT Yuan - The Journal of Organic Chemistry, 2010 - ACS Publications
The palladium-catalyzed ortho-alkoxylation of N-methoxybenzamides has been
demonstrated. With the CONHOMe group as a directing group, the aromatic C− H bond can …
demonstrated. With the CONHOMe group as a directing group, the aromatic C− H bond can …