Cancer vaccines in the clinic

ME Janes, AP Gottlieb, KS Park, Z Zhao… - Bioengineering & …, 2024 - Wiley Online Library
Vaccines are an important tool in the rapidly evolving repertoire of immunotherapies in
oncology. Although cancer vaccines have been investigated for over 30 years, very few …

Activation of STING in the pancreatic tumor microenvironment: a novel therapeutic opportunity

H Chamma, IK Vila, C Taffoni, A Turtoi, N Laguette - Cancer Letters, 2022 - Elsevier
Pancreatic ductal adenocarcinoma (PDAC) is a cancer of poor prognosis that presents with
a dense desmoplastic stroma that contributes to therapeutic failure. PDAC patients are …

Role of targeted immunotherapy for pancreatic ductal adenocarcinoma (PDAC) treatment: An overview

K Panchal, RK Sahoo, U Gupta… - International …, 2021 - Elsevier
Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest solid tumors with a high
mortality rate and poor survival rate. Depending on the tumor stage, PDAC is either treated …

Challenges and future perspectives of immunotherapy in pancreatic cancer

AM Wandmacher, A Letsch, S Sebens - Cancers, 2021 - mdpi.com
Simple Summary Immunotherapeutic agents harness the patient's immune system to fight
cancer cells. Especially immune checkpoint inhibitors, a certain group of immunotherapeutic …

Recent advances and future perspective of DC-based therapy in NSCLC

IAE van der Hoorn, G Flórez-Grau… - Frontiers in …, 2021 - frontiersin.org
Current treatment for patients with non-small-cell lung cancer (NSCLC) is suboptimal since
therapy is only effective in a minority of patients and does not always induce a long-lasting …

Reviewing the significance of dendritic cell vaccines in interrupting breast cancer development

N Gautam, G Ramamoorthi, N Champion… - Molecular Aspects of …, 2024 - Elsevier
Breast cancer is a heterogeneous disease and is the most prevalent cancer in women.
According to the US breast cancer statistics, about 1 in every 8 women develop an invasive …

[PDF][PDF] Dendritic cell vaccination combined with irreversible electroporation for treating pancreatic cancer—a narrative review

Z Zhang, G Yu, A Eresen, Z Chen, Z Yu… - Annals of …, 2024 - cdn.amegroups.cn
Key Content and Findings: IRE ablation destructs tumor structure while preserving
extracellular matrix and blood vessels facilitating local inflammation. The studies …

Research Progress on Liposome Pulmonary Delivery of Mycobacterium tuberculosis Nucleic Acid Vaccine and Its Mechanism of Action

D Zhang, H Zhao, P Li, X Wu, Y Liang - Journal of Aerosol Medicine …, 2024 - liebertpub.com
Traditional vaccines have played an important role in the prevention and treatment of
infectious diseases, but they still have problems such as low immunogenicity, poor stability …

[PDF][PDF] 胰腺导管腺癌的免疫治疗研究进展

W Puxiongzhi, YU Xinzhe, SHI Xiangjun, Y Zhou - 中国普通外科杂志, 2021 - zpwz.net
摘要胰腺导管腺癌(PDAC) 是常见的消化系统恶性肿瘤, 恶性程度高, 容易发生转移,
手术切除率低. 近年来, 以程序性细胞死亡蛋白1/程序性死亡配体1 (PD-1/PD-L1) …