Climate-sensitive infectious disease modelling is crucial for public health planning and is
underpinned by a complex network of software tools. We identified only 37 tools that …

Proposed genetic approaches for reducing human malaria include population modification,
which introduces genes into vector mosquitoes to reduce or prevent parasite transmission …

Synthetic gene drive (GD) systems constitute a form of novel invasive environmental
biotechnology with far-reaching consequences beyond those of other known genetically …

Controlling the principal African malaria vector, the mosquito Anopheles gambiae, is
considered essential to curtail malaria transmission. However, existing vector control …

The ability to engineer gene drives (genetic elements that bias their own inheritance) has
sparked enthusiasm and concerns. Engineered gene drives could potentially be used to …

Gene drives have shown great promise for suppression of pest populations. These
engineered alleles can function by a variety of mechanisms, but the most common is the …

Genetic surveillance of mosquito populations is becoming increasingly relevant as genetics-
based mosquito control strategies advance from laboratory to field testing. Especially …

Various environmental drivers influence life processes of insect vectors that transmit human
disease. Life histories observed under experimental conditions can reveal such complex …

The Ross-Macdonald model has exerted enormous influence over the study of malaria
transmission dynamics and control, but it lacked features to describe parasite dispersal …

Pandemic management requires that scientists rapidly formulate and analyse
epidemiological models in order to forecast the spread of disease and the effects of …