A Self‐Adaptive Pyroptosis Inducer: Optimizing the Catalytic Microenvironment of Nanozymes by Membrane‐Adhered Microbe Enables Potent Cancer …

W Wang, L Zhang, Y Zhang, X Liu, A Song… - Advanced …, 2024 - Wiley Online Library
Pyroptosis has garnered increasing attention in cancer immunotherapy. Moreover,
increasing plasma membrane damage by reactive oxygen species (ROS) is considered an …

Smart Bioorthogonal Nanozymes: From Rational Design to Appropriate Bioapplications

W Zhang, J Zhu, J Ren, X Qu - Advanced Materials, 2024 - Wiley Online Library
Bioorthogonal chemistry has provided an elaborate arsenal to manipulate native biological
processes in living systems. As the great advancement of nanotechnology in recent years …

Aggregation-Induced Emission: Application in Diagnosis and Therapy of Hepatocellular Carcinoma

W Xu, D Jian, H Yang, W Wang, Y Ding - Biosensors and Bioelectronics, 2024 - Elsevier
Hepatocellular carcinoma (HCC) is a serious health issue due to its low early diagnosis rate,
resistance to chemotherapy, and poor five-year survival rate. Therefore, it is crucial to …

A Gene‐Editable Palladium‐Based Bioorthogonal Nanoplatform Facilitates Macrophage Phagocytosis for Tumor Therapy

S Feng, Y Zhang, Y Gao, Y Liu, Y Wang… - Angewandte …, 2023 - Wiley Online Library
Macrophage phagocytosis of tumor cells has emerged as an attractive strategy for tumor
therapy. Nevertheless, immunosuppressive M2 macrophages in the tumor …

Lysosomal Rupture‐Mediated “Broken Window Effect” to Amplify Cuproptosis and Pyroptosis for High‐Efficiency Cancer Immunotherapy

G Zhu, M Wang, L Qiao, Y Xie, J Wang… - Advanced Functional …, 2024 - Wiley Online Library
Autophagy, a lysosome‐involved degradation pathway, as a self‐protective cellular process,
always weakens the efficiency of tumor therapies. Herein, for the first time, the …

Fluorinated Titanium Oxide (TiO2–xFx) Nanospindles as Ultrasound-Triggered Pyroptosis Inducers to Boost Sonodynamic Immunotherapy

S Sun, X Huang, N Yang, H Lei, Z Pei, Z Han, L Liu… - ACS …, 2024 - ACS Publications
Pyroptosis is an inflammatory form of programmed cell death associated with the immune
system that can be induced by reactive oxygen species (ROS). As a therapeutic strategy with …

Multifunctional Copper‐Phenolic Nanopills Achieve Comprehensive Polyamines Depletion to Provoke Enhanced Pyroptosis and Cuproptosis for Cancer …

G Zhu, Y Xie, J Wang, M Wang, Y Qian… - Advanced …, 2024 - Wiley Online Library
The overexpression of polyamines in tumor cells contributes to the establishment of
immunosuppressive microenvironment and facilitates tumor growth. Here, it have …

An Alkaline Nanocage Continuously Activates Inflammasomes by Disrupting Multiorganelle Homeostasis for Efficient Pyroptosis

A Song, W Wang, H Wang, Y Ji, Y Zhang… - … Applied Materials & …, 2024 - ACS Publications
Pyroptosis has garnered increasing attention because of its ability to trigger robust antitumor
immunity. Pyroptosis is initiated by the activation of inflammasomes, which are regulated by …

Hypoxia-accelerating pyroptosis nanoinducers for promoting image-guided cancer immunotherapy

D Liu, M Liang, Y Tao, H Liu, Q Liu, W Bing, W Li, J Qi - Biomaterials, 2024 - Elsevier
Precise image-guided cancer immunotherapy holds immense potential in revolutionizing
cancer treatment. The strategies facilitating activatable imaging and controlled therapeutics …

Reversible Modulation of Cell–Cell Interactions Using Electrochemistry

Y Qiao, L Wang, W Xu, P Yang, C Tang… - … Applied Materials & …, 2024 - ACS Publications
Cell–cell interactions play an important role in many biological processes, and various
methods have been developed for controlling the cell–cell interactions. However, the …