Therapeutic drug monitoring of antiepileptic drugs: current status and future prospects

C Johannessen Landmark… - Expert opinion on …, 2020 - Taylor & Francis
ABSTRACT Introduction: Antiepileptic drugs (AEDs) are the cornerstone of treatment of
patients with epilepsy, and there are presently 27 licensed AEDs making AEDs among the …

Antiepileptic drug interactions-principles and clinical implications

SI Johannessen… - Current …, 2010 - ingentaconnect.com
Antiepileptic drugs (AEDs) are widely used as long-term adjunctive therapy or as
monotherapy in epilepsy and other indications and consist of a group of drugs that are …

Trends in prescriptions and costs of drugs for mental disorders in England, 1998–2010

S Ilyas, J Moncrieff - The British Journal of Psychiatry, 2012 - cambridge.org
BackgroundIncreasing rates of prescriptions for antidepressants, antipsychotics and
stimulants have been reported from various countries. AimsTo examine trends in …

Trends in the utilisation of psychotropic medications in Australia from 2000 to 2011

CP Stephenson, E Karanges… - Australian & New …, 2013 - journals.sagepub.com
Objective: This study examined longitudinal trends in the dispensing of psychotropic
medications in Australia from January 2000 to December 2011. Method: Dispensing data for …

Narrative review of topiramate: clinical uses and pharmacological considerations

NZ Pearl, CP Babin, NT Catalano, JC Blake… - Advances in …, 2023 - Springer
Due to the diverse mechanisms of action of antiseizure drugs, there has been a rise in
prescriptions of these drugs for non-epileptic pathologies. One drug that is now being used …

Drug interactions involving the new second-and third-generation antiepileptic drugs

C Johannessen Landmark… - Expert review of …, 2010 - Taylor & Francis
During the period 1989–2009, 14 new antiepileptic drugs (AEDs) were licensed for clinical
use and these can be subdivided into new second-and third-generation AEDs. The second …

The burden of severely drug-refractory epilepsy: a comparative longitudinal evaluation of mortality, morbidity, resource use, and cost using German health insurance …

A Strzelczyk, C Griebel, W Lux, F Rosenow… - Frontiers in …, 2017 - frontiersin.org
Purpose To evaluate long-term outcome of three years and treatment patterns of patients
suffering from severely drug-refractory epilepsy (SDRE). Methods This analysis was …

Reference ranges for antiepileptic drugs revisited: a practical approach to establish national guidelines

A Reimers, JA Berg, ML Burns, E Brodtkorb… - Drug design …, 2018 - Taylor & Francis
Background and objective Laboratories sometimes use different reference ranges for the
same antiepileptic drug (AED), particularly for new and poorly investigated drugs. This may …

Prevalence, utilization, and costs of antiepileptic drugs for epilepsy in Germany—a nationwide population-based study in children and adults

HM Hamer, R Dodel, A Strzelczyk… - Journal of …, 2012 - Springer
Nationwide analyses of drug use can provide a prevalence estimate of the underlying
disease and can help in understanding the characteristics of treatment. This study aimed for …

Host factors affecting antiepileptic drug delivery—pharmacokinetic variability

CJ Landmark, SI Johannessen, T Tomson - Advanced drug delivery …, 2012 - Elsevier
Antiepileptic drugs (AEDs) are the mainstay in the treatment of epilepsy, one of the most
common serious chronic neurological disorders. AEDs display extensive pharmacological …