The role of ligands in the chemical synthesis and applications of inorganic nanoparticles

A Heuer-Jungemann, N Feliu, I Bakaimi… - Chemical …, 2019 - ACS Publications
The design of nanoparticles is critical for their efficient use in many applications ranging from
biomedicine to sensing and energy. While shape and size are responsible for the properties …

DNA nanotechnology-enabled drug delivery systems

Q Hu, H Li, L Wang, H Gu, C Fan - Chemical reviews, 2018 - ACS Publications
Over the past decade, we have seen rapid advances in applying nanotechnology in
biomedical areas including bioimaging, biodetection, and drug delivery. As an emerging …

Gold nanoparticles in cancer treatment

K Sztandera, M Gorzkiewicz… - Molecular …, 2018 - ACS Publications
Colloidal gold has been studied for its potential application in medicine for centuries.
However, synthesis and evaluation of various gold nanoparticles have only recently been …

Analysis of nanoparticle delivery to tumours

S Wilhelm, AJ Tavares, Q Dai, S Ohta, J Audet… - Nature reviews …, 2016 - nature.com
Targeting nanoparticles to malignant tissues for improved diagnosis and therapy is a
popular concept. However, after surveying the literature from the past 10 years, only …

Nanoparticle probes for the detection of cancer biomarkers, cells, and tissues by fluorescence

AB Chinen, CM Guan, JR Ferrer, SN Barnaby… - Chemical …, 2015 - ACS Publications
Cancer is the second most common cause of death in the United States, trailing only heart
disease in incidence. Despite significant worldwide investment in research, cancer remains …

Identifying cell receptors for the nanoparticle protein corona using genome screens

W Ngo, JLY Wu, ZP Lin, Y Zhang, B Bussin… - Nature Chemical …, 2022 - nature.com
Nanotechnology provides platforms to deliver medical agents to specific cells. However, the
nanoparticle's surface becomes covered with serum proteins in the blood after …

Engineered nanoparticles for drug delivery in cancer therapy

T Sun, YS Zhang, B Pang, DC Hyun… - Nanomaterials and …, 2021 - taylorfrancis.com
In medicine, nanotechnology has sparked a rapidly growing interest as it promises to solve a
number of issues associated with conventional therapeutic agents, including their poor …

DNA-functionalized metal–organic framework nanoparticles for intracellular delivery of proteins

S Wang, Y Chen, S Wang, P Li, CA Mirkin… - Journal of the …, 2019 - ACS Publications
Due to their large size, charged surfaces, and environmental sensitivity, proteins do not
naturally cross cell-membranes in intact form and, therefore, are difficult to deliver for both …

Identifying trends in gold nanoparticle toxicity and uptake: size, shape, capping ligand, and biological corona

C Carnovale, G Bryant, R Shukla, V Bansal - ACS omega, 2019 - ACS Publications
The drive behind the growing interest in understanding gold nanoparticle (AuNP) cytotoxicity
originates from the promise of AuNPs for diverse biological applications across the fields of …

DNA nanostructures: current challenges and opportunities for cellular delivery

A Lacroix, HF Sleiman - ACS nano, 2021 - ACS Publications
DNA nanotechnology has produced a wide range of self-assembled structures, offering
unmatched possibilities in terms of structural design. Because of their programmable …