Over the last two decades, we have witnessed a revolution in the field of Parkinson's
disease (PD) genetics. Great advances have been made in identifying many loci that confer …

Almost two decades of genetic research in Parkinson's disease (PD) have remarkably
increased our knowledge regarding the genetic basis of PD with numerous genes and …

Genetic variation around the LRRK2 gene affects risk of both familial and sporadic
Parkinson's disease (PD). However, the biological functions of LRRK2 remain incompletely …

Parkinson's disease (PD) is a common motor disorder of mysterious etiology. It is due to the
progressive degeneration of the dopaminergic neurons of the substantia nigra and is …

Research in Parkinson's disease (PD) genetics has been extremely prolific over the past
decade. More than 13 loci and 9 genes have been identified, but their implication in PD is …

The cause of Parkinson's disease (PD) remains unknown in most patients. Since 1997, with
the first genetic mutation known to cause PD described in SNCA gene, many other genes …

There has been tremendous progress toward understanding the genetic basis of
Parkinson's disease and related movement disorders. We summarize the genetic, clinical …

To the Editor: Parkinson's disease is characterized by resting tremor, rigidity, and
bradykinesia caused by the loss of dopaminergic neurons in the substantia nigra, a good …

Activity-dependent modifications in synaptic efficacy, such as long-term depression (LTD)
and long-term potentiation (LTP), represent key cellular substrates for adaptive motor control …

Parkinson's disease (PD) is the most common motor neurodegenerative disease. Mutations
in the gene encoding leucine-rich repeat kinase 2 (LRRK2) have been linked recently with …