The current management of patients with primary psychosis worldwide is often remarkably
stereotyped. In almost all cases an antipsychotic medication is prescribed, with second …

Children of people with severe mental illness are a largely neglected, yet identifiable,
population at biopsychosocial risk for reduced well-being and poor mental health. Outside of …

Background Limited studies have been conducted to explore the interaction effects of social
environmental and genetic factors on the risks of common psychiatric disorders. Methods …

The polygenic risk score (PRS) allows for quantification of the relative contributions of genes
and environment in population-based studies of mental health. We analyzed the impact of …

Objectives Childhood trauma increases the risk of developing mental illness as does being
born to parents with schizophrenia or bipolar disorder. We aimed to compare prevalence of …

Humanitarian psychiatry is the provision of services for mental health and psychosocial
support in a humanitarian context–that is, to populations exposed to collective violence …

Objective Parental severe mental illness (SMI) increases the lifetime risk of mental and
pediatric disorders in the offspring but little is known about specific disorders during early …

Background Exposure to inadequate home environment may put the healthy development of
familial high-risk children at risk. This study aimed to investigate associations between risk …

Objective: Children of parents with severe mental illness are at increased risk of mental
illness throughout their lifespan due to complex gene–environment interactions. Preventive …

Background Children born to parents with severe mental illness have gained more attention
during the last decades because of increasing evidence documenting that these children …