[HTML][HTML] Metabolomics in diabetes and diabetic complications: insights from epidemiological studies
Q Jin, RCW Ma - Cells, 2021 - mdpi.com
The increasing prevalence of diabetes and its complications, such as cardiovascular and
kidney disease, remains a huge burden globally. Identification of biomarkers for the …
kidney disease, remains a huge burden globally. Identification of biomarkers for the …
Genetic correlations of polygenic disease traits: from theory to practice
W Van Rheenen, WJ Peyrot, AJ Schork… - Nature Reviews …, 2019 - nature.com
The genetic correlation describes the genetic relationship between two traits and can
contribute to a better understanding of the shared biological pathways and/or the causality …
contribute to a better understanding of the shared biological pathways and/or the causality …
Effect of evolocumab on progression of coronary disease in statin-treated patients: the GLAGOV randomized clinical trial
Importance Reducing levels of low-density lipoprotein cholesterol (LDL-C) with intensive
statin therapy reduces progression of coronary atherosclerosis in proportion to achieved …
statin therapy reduces progression of coronary atherosclerosis in proportion to achieved …
Coronary Atherosclerotic Plaque Regression: JACC State-of-the-Art Review
LP Dawson, M Lum, N Nerleker, SJ Nicholls… - Journal of the American …, 2022 - jacc.org
Over the last 3 decades there have been substantial improvements in treatments aimed at
reducing cardiovascular (CV) events. As these treatments have been developed, there have …
reducing cardiovascular (CV) events. As these treatments have been developed, there have …
[HTML][HTML] Plant-based nutrition: Exploring health benefits for atherosclerosis, chronic diseases, and metabolic syndrome—A comprehensive review
Atherosclerosis, chronic non-communicable diseases, and metabolic syndrome are highly
interconnected and collectively contribute to global health concerns that reduce life …
interconnected and collectively contribute to global health concerns that reduce life …
Impact of statins on serial coronary calcification during atheroma progression and regression
R Puri, SJ Nicholls, M Shao, Y Kataoka, K Uno… - Journal of the American …, 2015 - jacc.org
Background: Statins can regress coronary atheroma and lower clinical events. Although pre-
clinical studies suggest procalcific effects of statins in vitro, it remains unclear if statins can …
clinical studies suggest procalcific effects of statins in vitro, it remains unclear if statins can …
[HTML][HTML] Obesity-related changes in high-density lipoprotein metabolism and function
JT Stadler, G Marsche - International journal of molecular sciences, 2020 - mdpi.com
In obese individuals, atherogenic dyslipidemia is a very common and important factor in the
increased risk of cardiovascular disease. Adiposity-associated dyslipidemia is characterized …
increased risk of cardiovascular disease. Adiposity-associated dyslipidemia is characterized …
Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials …
Objective To investigate the effects on cardiovascular outcomes of drug interventions that
increase high density lipoprotein levels. Design Meta-analysis. Studies reviewed …
increase high density lipoprotein levels. Design Meta-analysis. Studies reviewed …
Effect of two intensive statin regimens on progression of coronary disease
Background Statins reduce adverse cardiovascular outcomes and slow the progression of
coronary atherosclerosis in proportion to their ability to reduce low-density lipoprotein (LDL) …
coronary atherosclerosis in proportion to their ability to reduce low-density lipoprotein (LDL) …
Effects of torcetrapib in patients at high risk for coronary events
PJ Barter, M Caulfield, M Eriksson… - New England journal …, 2007 - Mass Medical Soc
Background Inhibition of cholesteryl ester transfer protein (CETP) has been shown to have a
substantial effect on plasma lipoprotein levels. We investigated whether torcetrapib, a potent …
substantial effect on plasma lipoprotein levels. We investigated whether torcetrapib, a potent …