Approximately one third of the human proteome contains metal cations, either in the form of
cofactors with catalytic functions or as structural support elements. 1, 2 To guarantee a …

This review summarizes the state-of-the-art synchrotron-based techniques for studying the
environmental health effects of heavy metals exposure. Synchrotron radiation based X-ray …

Trace elements are chemical elements in minute quantities, which are known to accumulate
in the bone. Cortical and trabecular bones consist of bone structural units (BSUs) such as …

Biocompatibility is a key issue in the development of new implant materials. In this context, a
novel class of biodegrading Mg implants exhibits promising properties with regard to …

Metals and metalloids play fundamental roles in many physiological processes in biological
systems, but imbalance of these elements in the body may cause many diseases, such as …

Microscopic X-ray fluorescence (micro-XRF) is a versatile tool in environmental analysis. We
review work done in this field from 2008 to 2010 and highlight new aspects. Overall, there is …

Strontium ranelate (SrR) is a relatively new treatment for osteoporosis. In this study we
investigated its potential impact on human bone material quality in transiliac bone biopsies …

Matrix-assisted laser desorption/ionisation mass spectrometric imaging (MALDI MSI) is a
technique that provides localized information on intact molecules in a sample. Micro X-ray …

The diagnosis of osteoporosis is based on low bone mineral density (BMD) and/or the
occurrence of fragility fractures. The majority of patients, however, have also abnormally low …

For the past several decades, synchrotron radiation has been extensively used to measure
the spatial distribution and chemical affinity of elements found in trace concentrations (< few …