Multidrug resistance (MDR) is the dominant cause of the failure of cancer chemotherapy.
The design of antitumor drugs that are able to evade MDR is rapidly evolving, showing that …

The last decade witnessed the great advances in the development of nanomedicines. As a
kind of attractive nanomedicine, carrier-free nanomedicines received extensive …

Employing combination therapy has become obligatory in cancer cases exhibiting high
tumor load, chemoresistant tumor population, and advanced disease stages. Realization of …

The use of multiple therapeutic agents in combination has become the primary strategy to
treat drug resistant cancers. However, administration of combinatorial regimens is limited by …

The brief history of photodynamic therapy (PDT) research has been focused on
photosensitizers (PSs) and light delivery was introduced recently. The appropriate PSs were …

The discovery of new molecular targets and the subsequent development of novel
anticancer agents are opening new possibilities for drug combination therapy as anticancer …

Nanotechnology has resulted in materials that have greatly improved the effectiveness of
drug delivery because of their ability to control matter on the nanoscale. Advanced forms of …

Nanoparticles as drug delivery systems enable unique approaches for cancer treatment.
Over the last two decades, a large number of nanoparticle delivery systems have been …

PEGylation, covalent attaching polyethylene glycol (PEG) polymers to therapeutic agents, is
one of the most promising techniques to improve the therapeutic effect of drugs. Initially, this …

Drug delivery technologies represent a vast and vital area of Research and Development.
The demand for innovative drug delivery systems continues to grow, and this growth …