Structural plasticity of the hippocampus in neurodegenerative diseases

PDE Weerasinghe-Mudiyanselage, MJ Ang… - International journal of …, 2022 - mdpi.com
Neuroplasticity is the capacity of neural networks in the brain to alter through development
and rearrangement. It can be classified as structural and functional plasticity. The …

Neuroprotective, neurogenic, and anticholinergic evidence of Ganoderma lucidum cognitive effects: Crucial knowledge is still lacking

DA Luz, AM Pinheiro… - Medicinal Research …, 2023 - Wiley Online Library
Ganoderma lucidum is a mushroom that has been widely used for centuries in Asian
countries for its antiaging properties. It is popularly known as “Ling Zhi,”“Reishi,” and …

Anoectochilus roxburghii flavonoids extract ameliorated the memory decline and reduced neuron apoptosis via modulating SIRT1 signaling pathway in senescent …

Z Zeng, C Chen, Y SiTu, Z Shen, Y Chen… - Journal of …, 2022 - Elsevier
Ethnopharmacological relevance Anoectochilus roxburghii (A. roxburghii) is a precious herb
and folk medicine in many Asian countries. It has been used traditionally to treat diabetes …

[HTML][HTML] Complex and regional-specific changes in the morphological complexity of GFAP+ astrocytes in middle-aged mice

H Bondi, V Bortolotto, PL Canonico, M Grilli - Neurobiology of aging, 2021 - Elsevier
During aging, alterations in astrocyte phenotype occur in areas associated with age-related
cognitive decline, including hippocampus. Previous work reported subregion-specific …

Decreased Hippocampal Neurogenesis in Aged Male Wistar Rats Is Not Associated with Memory Acquisition in a Water Maze

M Stepanichev, V Aniol, N Lazareva… - International Journal of …, 2023 - mdpi.com
Brain aging is associated with a progressive decrease in learning abilities, memory,
attention, decision making, and sensory perception. Age-related cognitive disturbances may …

Targeting the Erk1/2 and autophagy signaling easily improved the neurobalst differentiation and cognitive function after young transient forebrain ischemia compared …

F Wang, Z Xia, P Sheng, Y Ren, J Liu, L Ding… - Cell Death …, 2022 - nature.com
The hippocampal neurogenesis occurs constitutively throughout adulthood in mammalian
species, but declines with age. In this study, we overtly found that the neuroblast proliferation …

[HTML][HTML] Age-associated gut microbiota impair hippocampus-dependent memory in a vagus-dependent manner

D Rei, S Saha, M Haddad, AH Rubio, BL Perlaza… - JCI insight, 2022 - ncbi.nlm.nih.gov
Aging is known to be associated with hippocampus-dependent memory decline, but the
underlying causes of this age-related memory impairment remain highly debated. Here, we …

Cutaneous burn injury induces neuroinflammation and reactive astrocyte activation in the hippocampus of aged mice

T Walrath, RH McMahan, JP Idrovo, N Quillinan… - Experimental …, 2022 - Elsevier
Background By 2050, one in six people globally will be 65 or older. Confusion and delirium
are significant complications after burn injury, especially in the elderly population. The …

Quantifying observational evidence for risk of dementia following androgen deprivation therapy for prostate cancer: An updated systematic review and meta-analysis

H Cui, Y Wang, F Li, G He, Z Jiang, X Gang… - Prostate Cancer and …, 2021 - nature.com
Background Androgen deprivation therapy (ADT) administration was recently reported and
might be positively associated with dementia. However, the existing studies showed …

Heart Rate Variability and Cognition: A Narrative Systematic Review of Longitudinal Studies

P Nicolini, G Malfatto, T Lucchi - Journal of Clinical Medicine, 2024 - mdpi.com
Background: Heart rate variability (HRV) is a reliable and convenient method to assess
autonomic function. Cross-sectional studies have established a link between HRV and …