The maintenance of memory plasma cells
L Khodadadi, Q Cheng, A Radbruch… - Frontiers in …, 2019 - frontiersin.org
It is now well accepted that plasma cells can become long-lived (memory) plasma cells and
secrete antibodies for months, years or a lifetime. However, the mechanisms involved in this …
secrete antibodies for months, years or a lifetime. However, the mechanisms involved in this …
Ectopic lymphoid neogenesis in rheumatic autoimmune diseases
Ectopic lymphoid neogenesis often occurs in the target tissues of patients with chronic
rheumatic autoimmune diseases such as rheumatoid arthritis, Sjögren syndrome and other …
rheumatic autoimmune diseases such as rheumatoid arthritis, Sjögren syndrome and other …
Regulation of immune responses and chronic inflammation by fibroblast-like synoviocytes
H Yoshitomi - Frontiers in immunology, 2019 - frontiersin.org
Synovial tissue is a membranous non-immune organ lining joint cavities where it supports
local immune responses, and functions directly and indirectly in joint destruction due to …
local immune responses, and functions directly and indirectly in joint destruction due to …
High-quality full-length immunoglobulin profiling with unique molecular barcoding
MA Turchaninova, A Davydov, OV Britanova… - Nature protocols, 2016 - nature.com
High-throughput sequencing analysis of hypermutating immunoglobulin (IG) repertoires
remains a challenging task. Here we present a robust protocol for the full-length profiling of …
remains a challenging task. Here we present a robust protocol for the full-length profiling of …
Ectopic lymphoid structures: powerhouse of autoimmunity
Ectopic lymphoid structures (ELS) often develop at sites of inflammation in target tissues of
autoimmune diseases, such as rheumatoid arthritis, Sjögren's syndrome, multiple sclerosis …
autoimmune diseases, such as rheumatoid arthritis, Sjögren's syndrome, multiple sclerosis …
[PDF][PDF] One year in review: the pathogenesis of rheumatoid arthritis
V Picerno, F Ferro, A Adinolfi, E Valentini… - Clin Exp …, 2015 - clinexprheumatol.org
The pathogenesis of rheumatoid arthritis (RA) is a complex scenario that, to date, is not fully
elucidated. However, scientific progress has enabled us to understand several mechanisms …
elucidated. However, scientific progress has enabled us to understand several mechanisms …
Sequencing the functional antibody repertoire—diagnostic and therapeutic discovery
WH Robinson - Nature Reviews Rheumatology, 2015 - nature.com
The development of high-throughput DNA sequencing technologies has enabled large-
scale characterization of functional antibody repertoires, a new method of understanding …
scale characterization of functional antibody repertoires, a new method of understanding …
Characterizing immune repertoires by high throughput sequencing: strategies and applications
JJA Calis, BR Rosenberg - Trends in immunology, 2014 - cell.com
As the key cellular effectors of adaptive immunity, T and B lymphocytes utilize specialized
receptors to recognize, respond to, and neutralize a diverse array of extrinsic threats. These …
receptors to recognize, respond to, and neutralize a diverse array of extrinsic threats. These …
Hunner-type (classic) interstitial cystitis: a distinct inflammatory disorder characterized by pancystitis, with frequent expansion of clonal B-cells and epithelial …
D Maeda, Y Akiyama, T Morikawa, A Kunita, Y Ota… - PloS one, 2015 - journals.plos.org
Interstitial cystitis (IC) is a chronic bladder disease with urinary frequency, bladder discomfort
or bladder pain of unknown etiology. Based on cystoscopic findings, patients with IC are …
or bladder pain of unknown etiology. Based on cystoscopic findings, patients with IC are …
Destructive roles of fibroblast-like synoviocytes in chronic inflammation and joint damage in rheumatoid arthritis
Fibroblast-like synoviocytes (FLSs) are important non-immune cells located mostly in the
inner layer of the synovium. Indeed, these cells are specialized mesenchymal cells …
inner layer of the synovium. Indeed, these cells are specialized mesenchymal cells …