Functional hydrogels for the treatment of myocardial infarction

T Wu, W Liu - NPG Asia Materials, 2022 - nature.com
Myocardial infarction (MI) is a major disease posing a significant threat to human health, as it
leads to necrosis of numerous cardiomyocytes (CMs), left ventricle dilation, and cardiac …

[HTML][HTML] Biomaterials to enhance stem cell transplantation

BN Kharbikar, P Mohindra, TA Desai - Cell Stem Cell, 2022 - cell.com
The successful transplantation of stem cells has the potential to transform regenerative
medicine approaches and open promising avenues to repair, replace, and regenerate …

Minimally invasive delivery of therapeutic agents by hydrogel injection into the pericardial cavity for cardiac repair

D Zhu, Z Li, K Huang, TG Caranasos, JS Rossi… - Nature …, 2021 - nature.com
Cardiac patches are an effective way to deliver therapeutics to the heart. However, such
procedures are normally invasive and difficult to perform. Here, we develop and test a …

Biomimetic Design of Mitochondria‐Targeted Hybrid Nanozymes as Superoxide Scavengers

Y Zhang, A Khalique, X Du, Z Gao, J Wu… - Advanced …, 2021 - Wiley Online Library
Abstract Development of enzyme mimics for the scavenging of excessive mitochondrial
superoxide (O2•−) can serve as an effective strategy in the treatment of many diseases …

An overview of the molecular mechanisms associated with myocardial ischemic injury: state of the art and translational perspectives

L Schirone, M Forte, L D'Ambrosio, V Valenti… - Cells, 2022 - mdpi.com
Cardiovascular disease is the leading cause of death in western countries. Among
cardiovascular diseases, myocardial infarction represents a life-threatening condition …

Nanomedicines for cardiovascular disease

BR Smith, ER Edelman - Nature Cardiovascular Research, 2023 - nature.com
The leading cause of death in the world, cardiovascular disease (CVD), remains a
formidable condition for researchers, clinicians and patients alike. CVD comprises a broad …

3D printing of tissue engineering scaffolds: a focus on vascular regeneration

P Wang, Y Sun, X Shi, H Shen, H Ning… - Bio-design and …, 2021 - Springer
Tissue engineering is an emerging means for resolving the problems of tissue repair and
organ replacement in regenerative medicine. Insufficient supply of nutrients and oxygen to …

A minimally invasive exosome spray repairs heart after myocardial infarction

J Yao, K Huang, D Zhu, T Chen, Y Jiang, J Zhang… - ACS …, 2021 - ACS Publications
Myocardial infarction (MI) remains the most common cause of death worldwide. Many MI
survivors will suffer from recurrent heart failure (HF), which has been recognized as a …

Ultra‐Histocompatible and Electrophysiological‐Adapted PEDOT‐Based Hydrogels Designed for Cardiac Repair

C Yu, Z Yue, H Zhang, M Shi, M Yao… - Advanced Functional …, 2023 - Wiley Online Library
Currently, although conducting polymers have exhibited potential electrophysiological
modulation, designing bioinspired ultra‐histocompatible conducting polymers remains a …

Exosome-loaded degradable polymeric microcapsules for the treatment of vitreoretinal diseases

H Bao, Y Tian, H Wang, T Ye, S Wang, J Zhao… - Nature Biomedical …, 2023 - nature.com
The therapeutic benefits of many cell types involve paracrine mechanisms. Inspired by the
paracrine functions of exosomes and the sustained degradation properties of …