This review article gives a comprehensive survey of the progress made in computational
modeling of the human atria during the last 10 years. Modeling the anatomy has emerged …

Abstract Cardiac digital twins (Cardiac Digital Twin (CDT) s) of human electrophysiology
(Electrophysiology (EP)) are digital replicas of patient hearts derived from clinical data that …

The importance and need for an integrative mathematical modeling approach in the
biological and medical fields is currently well recognized. Such an approach is crucial in …

Abstract Concepts that draw inspiration from soft biological tissues have enabled significant
advances in creating artificial materials for a range of applications, such as dry adhesives …

Mechanistic cardiac electrophysiology models allow for personalized simulations of the
electrical activity in the heart and the ensuing electrocardiogram (ECG) on the body surface …

The most important ECG marker for the diagnosis of ischemia or infarction is a change in the
ST segment. Baseline wander is a typical artifact that corrupts the recorded ECG and can …

In the chronic stage of myocardial infarction, a significant number of patients develop life-
threatening ventricular tachycardias (VT) due to the arrhythmogenic nature of the remodeled …

Atrial arrhythmias, and specifically atrial fibrillation (AF), induce rapid and irregular activation
patterns that appear on the torso surface as abnormal P-waves in electrocardiograms and …

Computer models capable of representing the intrinsic personal electrophysiology (EP) of
the heart in silico are termed virtual heart technologies. When anatomy and EP are tailored …

Realistic electrocardiogram (ECG) simulation with numerical models is important for
research linking cellular and molecular physiology to clinically observable signals, and …