Background The optimal management of major bleeding in patients receiving vitamin K
antagonists (VKA) for venous thromboembolism (VTE) is unclear. Methods We used the …

Objectives: This study aimed to investigate the efficacy of vitamin K1 in patients undergoing
HSCT and find a feasible and safe option for HSCT patients to prevent bleeding. Methods: A …

Background Cefoperazone/sulbactam is commonly prescribed for the treatment of infected
patients with cirrhosis. Aim To investigate the effect of cefoperazone/sulbactam on …

Purpose Vitamin K (phytonadione) is a commonly used first-line reversal agent for vitamin K
antagonist (VKA) therapy in patients presenting with a supratherapeutic international …

Background Vitamin K antagonists (eg, warfarin) remain the mainstay of anticoagulation
therapy in the United States, with over 22 million prescriptions being filled annually …

Abstract Objectives The American College of Chest Physicians (ACCP) provides guidelines
for the management of excessive anticoagulation in patients receiving warfarin. This multi …

The article discusses the best reversal options for warfarin-induced anticoagulation. It
recommends to withhold warfarin therapy and recheck international normalized ratio (INR) …

Background A substantial proportion of patients with cardiovascular diseases use dietary
supplements in anticipation of benefit. This also poses risks of adverse events from …

This institutional review board–approved retrospective cohort study evaluated the impact of
intravenous versus subcutaneous phytonadione on length of stay in hospitalized patients …

Warfarin is one of the most effective agents for prevention and treatment of venous and
arterial thrombosis but may cause bleeding, especially if OverdOsed." To minimize the risk …