Once myocardium dies during a heart attack, it is replaced by scar tissue over the course of
several weeks. The size, location, composition, structure and mechanical properties of the …

Living systems can grow, develop, adapt, and evolve. These phenomena are non-intuitive to
traditional engineers and often difficult to understand. Yet, classical engineering tools can …

The heart pumps blood to maintain circulation and ensure the delivery of oxygenated blood
to all the organs of the body. Mechanics play a critical role in governing and regulating heart …

Injectable biomaterials are an attractive therapy to attenuate left ventricular (LV) remodeling
after myocardial infarction (MI). Although studies have shown that injectable hydrogels …

Tissue engineering has emerged as a viable approach to treat disease or repair damage in
tissues and organs. One of the key elements for the success of tissue engineering is the use …

A central problem in biomechanical studies of personalized human left ventricular (LV)
modelling is to estimate material properties from in vivo clinical measurements. In this work …

Heart failure is a significant clinical issue. It is the cause of enormous healthcare costs
worldwide and results in significant morbidity and mortality. Cardiac regenerative therapy …

In this research, we hypothesized that novel biomechanical parameters are discriminative in
patients following acute ST-segment elevation myocardial infarction (STEMI). To identify …

Scaffolds for cardiac patch application must meet stringent requirements such as
biocompatibility, biodegradability, and facilitate vascularization in the engineered tissue …

Intramyocardial biomaterial injection therapy for myocardial infarction has made significant
progress since concept initiation more than 10 years ago. The interim successes and …