Nano-and micromotors are nano-and microscale devices, respectively, designed to perform
selected mechanical movements (eg, rotation, rolling, shuttling, delivery, contraction, and …

The ability to obtain a molecular-level understanding of the chemistry that takes place at
liquid/solid interfaces is key to the development and improvement of many chemical and …

In prokaryotes, translation can occur on mRNA that is being transcribed in a process called
coupling. How the ribosome affects the RNA polymerase (RNAP) during coupling is not well …

Transcription of highly expressed genes has been shown to occur in stochastic bursts. But
the origin of such ubiquitous phenomenon has not been understood. Here, we present the …

The basic features of DNA were elucidated during the half-century following the discovery of
the double helix. But it is only during the past decade that researchers have been able to …

During the past decade, physical techniques such as optical tweezers and atomic force
microscopy were used to study the mechanical properties of DNA at the single-molecule …

▪ Abstract Mechanical processes are involved in nearly every facet of the cell cycle.
Mechanical forces are generated in the cell during processes as diverse as chromosomal …

We imaged transcription in living cells using a locus-specific reporter system, which allowed
precise, single-cell kinetic measurements of promoter binding, initiation and elongation …

Abstract Knowledge of the elastic properties of DNA is required to understand the structural
dynamics of cellular processes such as replication and transcription. Measurements of force …

I review single-molecule experiments (SMEs) in biological physics. Recent technological
developments have provided the tools to design and build scientific instruments of high …