Sex determination, gonadal sex differentiation, and plasticity in vertebrate species

Y Nagahama, T Chakraborty… - Physiological …, 2021 - journals.physiology.org
A diverse array of sex determination (SD) mechanisms, encompassing environmental to
genetic, have been found to exist among vertebrates, covering a spectrum from fixed SD …

Sex determination mechanisms and sex control approaches in aquaculture animals

XY Li, J Mei, CT Ge, XL Liu, JF Gui - Science China Life Sciences, 2022 - Springer
Aquaculture is one of the most efficient modes of animal protein production and plays an
important role in global food security. Aquaculture animals exhibit extraordinarily diverse …

Vertebrate sex determination: evolutionary plasticity of a fundamental switch

B Capel - Nature Reviews Genetics, 2017 - nature.com
The discovery of the Sry gene in 1990 triggered a revolution in our understanding of sex
determination. More recently, advances in non-model organisms have been fuelled by the …

The histone demethylase KDM6B regulates temperature-dependent sex determination in a turtle species

C Ge, J Ye, C Weber, W Sun, H Zhang, Y Zhou, C Cai… - Science, 2018 - science.org
Temperature-dependent sex determination is a notable model of phenotypic plasticity. In
many reptiles, including the red-eared slider turtle Trachemys scripta elegans (T. scripta) …

Temperature-dependent sex determination is mediated by pSTAT3 repression of Kdm6b

C Weber, Y Zhou, JG Lee, LL Looger, G Qian, C Ge… - Science, 2020 - science.org
In many reptiles, including the red-eared slider turtle Trachemys scripta elegans (T. scripta),
sex is determined by ambient temperature during embryogenesis. We previously showed …

A conserved kinase-based body-temperature sensor globally controls alternative splicing and gene expression

T Haltenhof, A Kotte, F De Bortoli, S Schiefer, S Meinke… - Molecular Cell, 2020 - cell.com
Homeothermic organisms maintain their core body temperature in a narrow, tightly
controlled range. Whether and how subtle circadian oscillations or disease-associated …

A brief review of vertebrate sex evolution with a pledge for integrative research: towards 'sexomics'

M Stöck, L Kratochvíl, H Kuhl… - … of the Royal …, 2021 - royalsocietypublishing.org
Triggers and biological processes controlling male or female gonadal differentiation vary in
vertebrates, with sex determination (SD) governed by environmental factors or simple to …

Dmrt1 induces the male pathway in a turtle species with temperature-dependent sex determination

C Ge, J Ye, H Zhang, Y Zhang, W Sun, Y Sang… - …, 2017 - journals.biologists.com
The molecular mechanism underlying temperature-dependent sex determination (TSD) has
been a long-standing mystery; in particular, the thermosensitive genetic triggers for gonadal …

Differential intron retention in Jumonji chromatin modifier genes is implicated in reptile temperature-dependent sex determination

IW Deveson, CE Holleley, J Blackburn… - Science …, 2017 - science.org
In many vertebrates, sex of offspring is determined by external environmental cues rather
than by sex chromosomes. In reptiles, for instance, temperature-dependent sex …

Improved biomarker discovery through a plot twist in transcriptomic data analysis

N Sánchez-Baizán, L Ribas, F Piferrer - BMC biology, 2022 - Springer
Background Transcriptomic analysis is crucial for understanding the functional elements of
the genome, with the classic method consisting of screening transcriptomics datasets for …