Assessment of resistance vessel function in human skeletal muscle: guidelines for experimental design, Doppler ultrasound, and pharmacology

JK Limberg, DP Casey, JD Trinity… - American Journal …, 2020 - journals.physiology.org
The introduction of duplex Doppler ultrasound almost half a century ago signified a
revolutionary advance in the ability to assess limb blood flow in humans. It is now widely …

Methods and considerations for the analysis and standardization of assessing muscle sympathetic nerve activity in humans

DW White, JK Shoemaker, PB Raven - Autonomic Neuroscience, 2015 - Elsevier
The technique of microneurography and the assessment of muscle sympathetic nerve
activity (MSNA) are used in laboratories throughout the world. The variables used to …

Impact of reduced daily physical activity on conduit artery flow-mediated dilation and circulating endothelial microparticles

LJ Boyle, DP Credeur, NT Jenkins… - Journal of applied …, 2013 - journals.physiology.org
Physical inactivity promotes the development of cardiovascular diseases. However, few data
exist examining the vascular consequences of short-term reductions in daily physical …

Exaggerated vasoconstriction to spontaneous bursts of muscle sympathetic nerve activity in healthy young black men

JR Vranish, SW Holwerda, BE Young, DP Credeur… - …, 2018 - Am Heart Assoc
Blacks have the highest prevalence of hypertension, putting them at greater risk of
cardiovascular disease and death. Previous studies have reported that, relative to whites …

Sympathetic transduction in humans: recent advances and methodological considerations

BE Young, JL Greaney, DM Keller… - American Journal of …, 2021 - journals.physiology.org
Ever since their origin more than one half-century ago, microneurographic recordings of
sympathetic nerve activity have significantly advanced our understanding of the generation …

Augmented pressor and sympathetic responses to skeletal muscle metaboreflex activation in type 2 diabetes patients

SW Holwerda, RM Restaino… - American Journal …, 2016 - journals.physiology.org
Previous studies have reported exaggerated increases in arterial blood pressure during
exercise in type 2 diabetes (T2D) patients. However, little is known regarding the underlying …

Age-and sex-related differences in sympathetic vascular transduction and neurohemodynamic balance in humans

AW D'Souza, SL Hissen, K Manabe… - American Journal …, 2023 - journals.physiology.org
Bursts of muscle sympathetic nerve activity (MSNA) and the ensuing vasoconstriction are
pivotal determinants of beat-by-beat blood pressure regulation. Although age and sex …

Sex differences in vascular transduction of sympathetic nerve activity

SL Hissen, CE Taylor - Clinical Autonomic Research, 2020 - Springer
Purpose Sympathetic vasoconstriction plays a major role in the beat-to-beat control of blood
pressure. To be effective and thus avoid dangerously high or low blood pressures, this …

[HTML][HTML] Influence of age and estradiol on sympathetic nerve activity responses to exercise in women

MM Wenner, JL Greaney, EL Matthews… - Medicine and science …, 2022 - ncbi.nlm.nih.gov
Methods. Herein, we tested the hypothesis that sympathetic responses during exercise are
augmented in PMW compared to young women (YW), and estradiol administration …

Fifty years of microneurography: learning the language of the peripheral sympathetic nervous system in humans

JK Shoemaker, SA Klassen… - Journal of …, 2018 - journals.physiology.org
As a primary component of homeostasis, the sympathetic nervous system enables rapid
adjustments to stress through its ability to communicate messages among organs and cause …