Myocardial interstitial fibrosis in hypertensive heart disease: from mechanisms to clinical management
A González, B López, S Ravassa, G San José… - …, 2024 - Am Heart Assoc
Hypertensive heart disease (HHD) can no longer be considered as the beneficial adaptive
result of the hypertrophy of cardiomyocytes in response to pressure overload leading to the …
result of the hypertrophy of cardiomyocytes in response to pressure overload leading to the …
Hypertensive Heart Disease: A Narrative Review Series—Part 2: Macrostructural and Functional Abnormalities
V Nemtsova, T Burkard, AS Vischer - Journal of Clinical Medicine, 2023 - mdpi.com
Hypertensive heart disease (HHD) remains a major global public health concern despite the
implementation of new approaches for the management of hypertensive patients. The …
implementation of new approaches for the management of hypertensive patients. The …
Blood immune cell alterations in patients with hypertensive left ventricular hypertrophy and heart failure with preserved ejection fraction
A Ovchinnikov, A Filatova, A Potekhina… - Journal of …, 2023 - mdpi.com
(1) Background: Chronic inflammation and fibrosis are key players in cardiac remodeling
associated with left ventricular hypertrophy (LVH) and heart failure with a preserved ejection …
associated with left ventricular hypertrophy (LVH) and heart failure with a preserved ejection …
Hypertensive Heart Disease: A Narrative Review Series—Part 3: Vasculature, Biomarkers and the Matrix of Hypertensive Heart Disease
V Nemtsova, AS Vischer, T Burkard - Journal of Clinical Medicine, 2024 - mdpi.com
Over the last few decades, research efforts have resulted in major advances in our
understanding of the pathophysiology of hypertensive heart disease (HHD). This is the third …
understanding of the pathophysiology of hypertensive heart disease (HHD). This is the third …
99mTc-HFAPi imaging identifies early myocardial fibrosis in the hypertensive heart
B Xie, L Li, M Lin, M Nanna, Y Su, C Hua… - Journal of …, 2023 - journals.lww.com
Background: This study aimed to explore whether 99m Tc-radiolabeled fibroblast activation
protein inhibitor (99m Tc-HFAPi) imaging can detect early myocardial fibrosis in the …
protein inhibitor (99m Tc-HFAPi) imaging can detect early myocardial fibrosis in the …
Possible Role of Gut Microbiota Alterations in Myocardial Fibrosis and Burden of Heart Failure in Hypertensive Heart Disease
B Pitt, J Diez - Hypertension, 2024 - Am Heart Assoc
Epidemiological studies have revealed that hypertensive heart disease is a major risk factor
for heart failure, and its heart failure burden is growing rapidly. The need to act in the face of …
for heart failure, and its heart failure burden is growing rapidly. The need to act in the face of …
Annexin A5 knockdown inhibits cardiomyocyte apoptosis and alleviates cardiac hypertrophy via activating the PI3K/AKT/Bcl-2 signaling pathway
L Zhao, H Cao, Y Yuan, C Liao, D Huang, X Li… - Scientific Reports, 2024 - nature.com
Abstract Annexin A5 (ANXA5) is a small calcium-dependent protein that binds specifically to
negatively charged phosphatidylserine as a marker of apoptosis. Previous studies have …
negatively charged phosphatidylserine as a marker of apoptosis. Previous studies have …
Challenges in Echocardiography for the Diagnosis and Prognosis of Non-Ischemic Hypertensive Heart Disease
NPE Kadoglou, A Mouzarou, N Hadjigeorgiou… - Journal of Clinical …, 2024 - mdpi.com
It has been well established that arterial hypertension is considered as a predominant risk
factor for the development of cardiovascular diseases. Despite the link between arterial …
factor for the development of cardiovascular diseases. Despite the link between arterial …
FOXO3 Longevity Genotype Mitigates Risk Posed by Hypertension on Incident Coronary Artery Disease in Middle-Aged Men: Kuakini Honolulu Heart Program
R Chen, BJ Morris, TA Donlon… - The Journals of …, 2024 - academic.oup.com
Background This study tested whether the carriage of the longevity-associated G-allele of
FOXO3 SNP rs2802292 (TG/GG) protects against incident coronary artery disease (CAD) in …
FOXO3 SNP rs2802292 (TG/GG) protects against incident coronary artery disease (CAD) in …
Effects of concurrent training and N-acetylcysteine supplementation on cardiac remodeling and oxidative stress in middle-aged spontaneously hypertensive rats
A Junqueira, MJ Gomes, ARR Lima… - BMC Cardiovascular …, 2024 - Springer
Background This study evaluated the effects of concurrent isolated training (T) or training
combined with the antioxidant N-acetylcysteine (NAC) on cardiac remodeling and oxidative …
combined with the antioxidant N-acetylcysteine (NAC) on cardiac remodeling and oxidative …