The nearly ubiquitous expression of endogenous 24 h oscillations known as circadian
rhythms regulate the timing of physiological functions in the body. These intrinsic rhythms …

Metabolic disorders result from dysregulation of central nervous system and peripheral
metabolic energy homeostatic pathways. To maintain normal energy balance, neural circuits …

Food intake follows a predictable daily pattern and synchronizes metabolic rhythms.
Neurons expressing agouti-related protein (AgRP) read out physiological energetic state …

The p75 neurotrophin receptor (p75 NTR) functions at the molecular nexus of cell death,
survival, and differentiation. In addition to its contribution to neurodegenerative diseases and …

Salient cues, such as the rising sun or availability of food, entrain biological clocks for
behavioral adaptation. The mechanisms underlying entrainment to food availability remain …

How dopamine signaling regulates biological rhythms is an area of emerging interest. Here
we review experiments focused on delineating dopamine signaling in the suprachiasmatic …

The relationship between hunger and subsequent feeding has undoubtedly provided strong
selective pressures that underpin motivation, learning and memory processes. Together …

The ability to tell time relative to predictable feeding opportunities has a long history of
research, going back more than 100 years with behavioral observations of honeybees and …

Locomotor activity is one of the most commonly assayed animal behaviors. It is the gold
standard for assessing behavioral circadian rhythmicity. Here, we develop a flexible and …

The human brain is the command center for the nervous system enabling thoughts, memory,
movement, and emotions through a complex function. The Microbiota-gut-brain axis is a …