An analytical review of the numerical methods used for finite element modeling of traumatic brain injury

JS Giudice, W Zeng, T Wu, A Alshareef… - Annals of biomedical …, 2019 - Springer
Dozens of finite element models of the human brain have been developed for providing
insight into the mechanical response of the brain during impact. Many models used in …

Stiffness and beyond: what MR elastography can tell us about brain structure and function under physiologic and pathologic conditions

Z Yin, AJ Romano, A Manduca, RL Ehman… - Topics in Magnetic …, 2018 - journals.lww.com
Brain magnetic resonance elastography (MRE) was developed on the basis of a desire to
“palpate by imaging” and is becoming a powerful tool in the investigation of …

Brain stiffens post mortem

J Weickenmeier, M Kurt, E Ozkaya, R de Rooij… - Journal of the …, 2018 - Elsevier
Alterations in brain rheology are increasingly recognized as a diagnostic marker for various
neurological conditions. Magnetic resonance elastography now allows us to assess brain …

MR Imaging of Human Brain Mechanics In Vivo: New Measurements to Facilitate the Development of Computational Models of Brain Injury

PV Bayly, A Alshareef, AK Knutsen, K Upadhyay… - Annals of biomedical …, 2021 - Springer
Computational models of the brain and its biomechanical response to skull accelerations
are important tools for understanding and predicting traumatic brain injuries (TBIs) …

[HTML][HTML] Mechanical stiffness and anisotropy measured by MRE during brain development in the minipig

S Wang, CA Guertler, RJ Okamoto, CL Johnson… - NeuroImage, 2023 - Elsevier
The relationship between brain development and mechanical properties of brain tissue is
important, but remains incompletely understood, in part due to the challenges in measuring …

Mechanical properties of porcine brain tissue in vivo and ex vivo estimated by MR elastography

CA Guertler, RJ Okamoto, JL Schmidt… - Journal of …, 2018 - Elsevier
The mechanical properties of brain tissue in vivo determine the response of the brain to
rapid skull acceleration. These properties are thus of great interest to the developers of …

Magnetic resonance elastography of the brain: a comparison between pigs and humans

J Weickenmeier, M Kurt, E Ozkaya… - Journal of the …, 2018 - Elsevier
Magnetic resonance elastography holds promise as a non-invasive, easy-to-use, in vivo
biomarker for neurodegenerative diseases. Throughout the past decade, pigs have gained …

Clinical application of magnetic resonance elastography in pediatric neurological disorders

AM Khair, G McIlvain, MDJ McGarry, V Kandula… - Pediatric …, 2023 - Springer
Magnetic resonance elastography is a relatively new, rapidly evolving quantitative magnetic
resonance imaging technique which can be used for mapping the viscoelastic mechanical …

Tension strain-softening and compression strain-stiffening behavior of brain white matter

F Eskandari, M Shafieian, MM Aghdam… - Annals of Biomedical …, 2021 - Springer
Brain, the most important component of the central nervous system (CNS), is a soft tissue
with a complex structure. Understanding the role of brain tissue microstructure in mechanical …

Insights into traumatic brain injury from MRI of harmonic brain motion

RJ Okamoto, AJ Romano… - Journal of …, 2019 - journals.sagepub.com
Measurements of dynamic deformation of the human brain, induced by external harmonic
vibration of the skull, were analyzed to illuminate the mechanics of mild traumatic brain …