Computational mechanisms of addiction and anxiety: a developmental perspective

N Goldway, E Eldar, G Shoval, CA Hartley - Biological psychiatry, 2023 - Elsevier
A central goal of computational psychiatry is to identify systematic relationships between
transdiagnostic dimensions of psychiatric symptomatology and the latent learning and …

The good, the bad, and the ugly—chances, challenges, and clinical implications of avoidance research in psychosomatic medicine

F Labrenz, ML Woud, S Elsenbruch… - Frontiers in Psychiatry, 2022 - frontiersin.org
Avoidance behaviors are shaped by associative learning processes in response to fear of
impending threats, particularly physical harm. As part of a defensive repertoire, avoidance is …

The association of PTSD symptom severity with amygdala nuclei volumes in traumatized youths

OT Ousdal, AM Milde, GS Hafstad, E Hodneland… - Translational …, 2020 - nature.com
The amygdala is a core component in neurobiological models of stress and stress-related
pathologies, including post-traumatic stress disorder (PTSD). While numerous studies have …

A primer on the use of computational modelling to investigate affective states, affective disorders and animal welfare in non-human animals

V Neville, M Mendl, ES Paul, P Seriès… - Cognitive, Affective, & …, 2024 - Springer
Objective measures of animal emotion-like and mood-like states are essential for preclinical
studies of affective disorders and for assessing the welfare of laboratory and other animals …

Suicidal thoughts and behaviors are associated with an increased decision-making bias for active responses to escape aversive states.

AJ Millner, HEM den Ouden, SJ Gershman… - Journal of abnormal …, 2019 - psycnet.apa.org
Suicide is a leading cause of death worldwide. Despite decades of clinical and theoretical
accounts that suggest that suicidal thoughts and behaviors are efforts to escape painful …

Change, stability, and instability in the Pavlovian guidance of behaviour from adolescence to young adulthood

M Moutoussis, ET Bullmore, IM Goodyer… - PLoS computational …, 2018 - journals.plos.org
Pavlovian influences are important in guiding decision-making across health and
psychopathology. There is an increasing interest in using concise computational tasks to …

Interindividual differences in Pavlovian influence on learning are consistent

S Saeedpour, MM Hossein… - Royal Society Open …, 2023 - royalsocietypublishing.org
Pavlovian influences impair instrumental learning. It is easier to learn to approach reward-
predictive signals and avoid punishment-predictive cues than their contrary. Whether the …

Adolescents exhibit reduced Pavlovian biases on instrumental learning

HA Raab, CA Hartley - Scientific reports, 2020 - nature.com
Multiple learning systems allow individuals to flexibly respond to opportunities and
challenges present in the environment. An evolutionarily conserved “Pavlovian” learning …

The trauma-informed ethical decision-making model: An integrative framework

CS Stark, JL Tapia-Fuselier Jr… - Journal of Trauma …, 2022 - journals.library.appstate.edu
Abstract The prevalence of Adverse Childhood Experiences, and recent increase in stress
during the COVID-19 crisis necessitates the practice of trauma-informed care in counseling …

Intermittent absence of control during reinforcement learning interferes with Pavlovian bias in action selection

G Csifcsák, E Melsæter, M Mittner - Journal of cognitive neuroscience, 2020 - direct.mit.edu
The ability to control the occurrence of rewarding and punishing events is crucial for our well-
being. Two ways to optimize performance are to follow heuristics like Pavlovian biases to …