Decades of research indicate mitochondria from Alzheimer's disease (AD) patients differ
from those of non-AD individuals. Initial studies revealed structural differences, and …

Ten years ago we first proposed the Alzheimer's disease (AD) mitochondrial cascade
hypothesis. This hypothesis maintains that gene inheritance defines an individual's baseline …

Objective To examine in a 3-year brain imaging study the effects of higher vs lower
adherence to a Mediterranean-style diet (MeDi) on Alzheimer disease (AD) biomarker …

Diffusion tensor imaging has been used extensively as a research tool to understand the
structural changes associated with white matter pathology. Using water diffusion as the …

Alzheimer's disease (AD) is an age-dependent neurodegenerative disorder associated with
progressive loss of cognitive function. 2-[18 F] fluoro-2-deoxy-d-glucose (FDG) positron …

Estrogens play a crucial physiological function in the brain; however, debates exist
concerning the role of estrogens in Alzheimer's disease (AD). Women during pre-, peri-, or …

Viable Alzheimer's disease (AD) hypotheses must account for its age-dependence;
commonality; association with amyloid precursor protein, tau, and apolipoprotein E biology; …

Structural brain changes have been described in both mild cognitive impairment (MCI) and
Alzheimer's disease (AD). However, less is known about whether structural changes are …

Significance: Mitochondria and brain bioenergetics are increasingly thought to play an
important role in Alzheimer's disease (AD). Recent Advances: Data that support this view are …

Objectives Epidemiological evidence linking diet, one of the most important modifiable
lifestyle factors, and risk of Alzheimer's disease (AD) is rapidly increasing. However, there is …