Possible therapeutic effects of Nigella sativa and its thymoquinone on COVID-19

MR Khazdair, S Ghafari, M Sadeghi - Pharmaceutical biology, 2021 - Taylor & Francis
Context COVID-19 is a novel coronavirus that causes a severe infection in the respiratory
system. Nigella sativa L.(Ranunculaceae) is an annual flowering plant used traditionally as …

[HTML][HTML] Thymoquinone as a potential adjuvant therapy for cancer treatment: evidence from preclinical studies

AGM Mostofa, MK Hossain, D Basak… - Frontiers in …, 2017 - frontiersin.org
Thymoquinone (TQ), the main bioactive component of Nigella sativa, has been found to
exhibit anticancer effects in numerous preclinical studies. Due to its multitargeting nature, TQ …

Black seed thymoquinone improved insulin secretion, hepatic glycogen storage, and oxidative stress in streptozotocin‐induced diabetic male wistar rats

HMA Abdelrazek, OE Kilany… - Oxidative medicine …, 2018 - Wiley Online Library
Diabetes mellitus is one of the metabolic diseases having several complications. Nigella
sativa oil (NSO) might have beneficial effects in the treatment of diabetic complications …

The protective effect of Nigella sativa extract on lung inflammation and oxidative stress induced by lipopolysaccharide in rats

A Mokhtari-Zaer, F Norouzi, VR Askari… - Journal of …, 2020 - Elsevier
Ethnopharmacological relevance Oxidative stress during inflammation can increase
inflammation and damage tissue. Nigella sativa L.(NS) showed many pharmacological …

[HTML][HTML] Chemopreventive and anticancer effects of thymoquinone: cellular and molecular targets

R Gomathinayagam, JH Ha, M Jayaraman… - Journal of cancer …, 2020 - ncbi.nlm.nih.gov
Thymoquinone (TQ) is a bioactive component derived from the seeds of Nigella sativa that
are commonly as black cumin. Evidences indicate that the medicinal properties of TQ have …

Thymoquinone increases the expression of neuroprotective proteins while decreasing the expression of pro-inflammatory cytokines and the gene expression NFκB …

MK Cobourne-Duval, E Taka, P Mendonca… - Journal of …, 2018 - Elsevier
Neuroinflammation and microglial activation are pathological markers of a number of central
nervous system (CNS) diseases. Chronic activation of microglia induces the release of …

Neuropharmacological potential and delivery prospects of thymoquinone for neurological disorders

MD Jakaria, DY Cho, M Ezazul Haque… - Oxidative medicine …, 2018 - Wiley Online Library
Thymoquinone (TQ) is an active ingredient isolated from Nigella sativa and has various
pharmacological activities, such as protection against oxidative stress, inflammation, and …

[HTML][HTML] Regressions of breast carcinoma syngraft following treatment with piperine in combination with thymoquinone

WH Talib - Scientia pharmaceutica, 2017 - mdpi.com
Thymoquinone (TQ) and piperine, the active ingredients in cumin (Nigella sativa) and black
pepper (Piper longum), respectively, exhibit various bioactivities including anticancer effects …

The influence of hydro-ethanolic extract of Portulaca oleracea L. on Th1/Th2 balance in isolated human lymphocytes

VR Askari, SA Rezaee, K Abnous, M Iranshahi… - Journal of …, 2016 - Elsevier
Ethnopharmacological relevance The anti-inflammatory and anti-oxidants activity of
Portulaca oleracea L.(P. oleracea) were mentioned in traditional texts. In previous studies …

[HTML][HTML] The Immunomodulatory Effect of Nigella sativa

K Ciesielska-Figlon, K Wojciechowicz, A Wardowska… - Antioxidants, 2023 - mdpi.com
Background: For thousands of years till nowadays, Nigella sativa (NS) has served as a
common spice and food preservative. Its seed extracts, seed oil, and essential oil in …