Molecular insight into invasive group A streptococcal disease

JN Cole, TC Barnett, V Nizet, MJ Walker - Nature Reviews Microbiology, 2011 - nature.com
Streptococcus pyogenes is also known as group A Streptococcus (GAS) and is an important
human pathogen that causes considerable morbidity and mortality worldwide. The GAS …

Interplay between group A Streptococcus and host innate immune responses

MSW Su, YL Cheng, YS Lin, JJ Wu - Microbiology and Molecular …, 2024 - Am Soc Microbiol
SUMMARY Group A Streptococcus (GAS), also known as Streptococcus pyogenes, is a
clinically well-adapted human pathogen that harbors rich virulence determinants …

Cariogenic bacteria degrade dental resin composites and adhesives

M Bourbia, D Ma, DG Cvitkovitch… - Journal of dental …, 2013 - journals.sagepub.com
A major reason for dental resin composite restoration replacement is related to secondary
caries promoted by acid production from bacteria including Streptococcus mutans (S …

Esterase from a cariogenic bacterium hydrolyzes dental resins

B Huang, WL Siqueira, DG Cvitkovitch, Y Finer - Acta biomaterialia, 2018 - Elsevier
Objectives To identify and characterize specific esterases from S. mutans with degradative
activity toward methacrylate-based resin monomers. Methods Out of several putative …

The group A Streptococcus small regulatory RNA FasX enhances streptokinase activity by increasing the stability of the ska mRNA transcript

E Ramirez‐Peña, J Treviño, Z Liu… - Molecular …, 2010 - Wiley Online Library
Small RNA molecules play key regulatory roles in many bacterial species. However, little
mechanistic data exists for the action of small regulatory RNAs in the human pathogen …

Genomic, transcriptomic, and proteomic insights into the symbiosis of deep-sea tubeworm holobionts

Y Yang, J Sun, Y Sun, YH Kwan, WC Wong… - The ISME …, 2020 - academic.oup.com
Deep-sea hydrothermal vents and methane seeps are often densely populated by animals
that host chemosynthetic symbiotic bacteria, but the molecular mechanisms of such host …

Self-assembled colloidal gel using cell membrane-coated nanosponges as building blocks

Y Zhang, W Gao, Y Chen, T Escajadillo, J Ungerleider… - ACS …, 2017 - ACS Publications
Colloidal gels consisting of oppositely charged nanoparticles are increasingly utilized for
drug delivery and tissue engineering. Meanwhile, cell membrane-coated nanoparticles are …

[HTML][HTML] Secreted extracellular virulence factors

W Hynes, M Sloan - 2016 - europepmc.org
Group A streptococci produce a wide variety of secreted extracellular products, many of
which are considered virulence factors. The number of these potential virulence factors …

Enterococcus faecalis hydrolyzes dental resin composites and adhesives

MQ Marashdeh, R Gitalis, C Levesque, Y Finer - Journal of endodontics, 2018 - Elsevier
Introduction After root canal treatment, the dentin-sealer interface undergoes degradation,
allowing for interfacial microbial biofilm proliferation and treatment failure. Saliva and …

Gene fitness landscape of group A streptococcus during necrotizing myositis

L Zhu, RJ Olsen, SB Beres, JM Eraso… - The Journal of …, 2019 - Am Soc Clin Investig
Necrotizing fasciitis and myositis are devastating infections characterized by high mortality.
Group A streptococcus (GAS) is a common cause of these infections, but the molecular …