Pharmacological potential of betulin as a multitarget compound

FO Adepoju, KC Duru, E Li, EG Kovaleva, MV Tsurkan - Biomolecules, 2023 - mdpi.com
Betulin is a natural triterpene, usually from birch bark, known for its potential wound-healing
properties. Despite having a wide range of pharmacological targets, no studies have …

α-Glucosidase and α-amylase inhibitory activities of medicinal plants in Thai antidiabetic recipes and bioactive compounds from Vitex glabrata R. Br. stem bark

S Thengyai, P Thiantongin, C Sontimuang… - Journal of herbal …, 2020 - Elsevier
Traditional medicines are currently still popular as an alternative in the treatment of diabetes
mellitus. However, the mechanism of action in lowering blood sugar of most folk recipes …

Plant products in the prevention of diabetes mellitus

AM Damić, S Jelena - Mini Reviews in Medicinal Chemistry, 2022 - ingentaconnect.com
The beneficial effect of plants in treating diabetes is not only well-known in traditional
medicine but also confirmed in numerous scientific studies. The basic platform for testing the …

Phyto-metabolomics of phlogacanthus thyrsiformis by using LC-ESI-QTOF-MS/MS and GC/QTOF-MS: Evaluation of antioxidant and enzyme inhibition potential of …

S Ponneganti, US Murty, C Bagul, RM Borkar… - Food Research …, 2022 - Elsevier
Phlogacanthus thyrsiformis (P. thyrsiformis) is a non-conventional edible plant that has been
used as a vegetable and as a traditional medicine to treat various diseases. This non …

A Multidirectional Perspective for Novel Functional Products: In vitro Pharmacological Activities and In silico Studies on Ononis natrix subsp. hispanica

S Yerlikaya, G Zengin, A Mollica, MC Baloglu… - Frontiers in …, 2017 - frontiersin.org
The genus Ononis has important value as traditional drugs and foods. In the present work,
we aimed to assess the chemical profiles and biological effects of Ononis natrix subsp …

[HTML][HTML] Antidiabetic activity of Ruellia tuberosa L., role of α-amylase inhibitor: in silico, in vitro, and in vivo approaches

DR Wulan, EP Utomo, C Mahdi - Biochemistry Research …, 2015 - ncbi.nlm.nih.gov
Ruellia tuberosa L. is a folk remedy in the treatment of diabetes mellitus. However, its
hypoglycemic activity has not been investigated so far. In the present study, the antidiabetic …

Evaluation of In Vitro α‐Amylase and α‐Glucosidase Inhibitory Potentials of 14 Medicinal Plants Constituted in Thai Folk Antidiabetic Formularies

C Somtimuang, OJ Olatunji… - Chemistry & …, 2018 - Wiley Online Library
The sporadic increase in the occurrence and prevalence of diabetes mellitus have
compelled and vigorous search for alternative anti‐diabetic therapeutic approach from …

In silico docking studies of α-amylase inhibitors from the anti-diabetic plant Leucas ciliata Benth. and an endophyte, Streptomyces longisporoflavus

JV Akshatha, HS SantoshKumar, HS Prakash… - 3 Biotech, 2021 - Springer
In this investigation, potential inhibitors of α-amylase, one of the key regulatory enzymes in
diabetes were characterized from the methanolic extract of Leucas ciliata …

In vitro and in silico insights of Cupressus sempervirens, Artemisia absinthium and Lippia triphylla: Bridging traditional knowledge and scientific validation

G Zengin, A Mollica, A Aktumsek, CMN Picot… - European Journal of …, 2017 - Elsevier
Introduction The search for new therapeutic agents for the management of diabetes mellitus
type 2 (DMT2) and neurodegenerative disorders coupled with the rising number of patients …

Penambatan Molekuler α, β, dan γ-mangostin Sebagai Inhibitor α-amilase Pankreas Manusia

N Gaspersz, MR Sohilait - Indonesian Journal of Chemical …, 2019 - ojs3.unpatti.ac.id
The in silico studies of interactions between the human pancreatic α-amylase (HPA) enzyme
to α, β, and γ-mangostin ligands has been carried out using the molecular docking method …