Malaria is an endemic disease that affected 229 million people and caused 409 thousand
deaths, in 2019. Disease control is based on early diagnosis and specific treatment with …

Malaria, transmitted through the bite of a Plasmodium-infected Anopheles mosquito,
remains a significant global health concern. This review examines the complex life cycle of …

Background Malaria is a public health menace. Resistance to therapeutic armamentarium is
impeding its control. Therefore, research targeting the discovery of novel antimalarial drug …

Background A major cumbersome factor in malaria control measure is the new coming
antimalarial drug resistance strains. The increase of resistance to the available marketed …

The artemisinin partial resistance is believed to be spread to artemisinin‐based combination
therapy partner drugs. As a result, new antiplasmodial compounds are required to treat …

Artemisinin and its derivatives have been commonly used to treat malaria. However, the
emergence of resistance against artemisinin derivatives has posed a critical challenge in …

Background The incidence of resistance among currently available antimalarial drugs, as
well as the high economic cost of malaria, has prompted researchers to look for novel …

Background. The evolution of resistance to currently used malaria medicines together with
the severe economic burden of malaria initiates the search for novel antimalarial drugs …

Remodeling the erythrocyte membrane and skeleton by the malarial parasite Plasmodium
falciparum is closely associated with intraerythrocytic development. However, the …

Background Despite the widely reported potentials of n-Hexadecanoic acid (HA) as a
bioactive, its multi-stage antiplasmodial activity and toxicity profiles remain largely unknown …