RASSF1A (Ras association domain family 1 isoform A) is a recently discovered tumor
suppressor whose inactivation is implicated in the development of many human cancers …

Head and neck cancer (HNC) is a heterogenous and complex entity including diverse
anatomical sites and a variety of tumor types displaying unique characteristics and different …

Background Runt-related transcription factor 3 (RUNX3) is a member of the runt-domain
family of transcription factors and has been reported to be a candidate tumor suppressor in …

Cumulative evidences show that Runt‐related transcription factor 3 (RUNX3) has a tumor
suppressive role in various cancers. In particular, RUNX3 appears to be an important …

Background: Aberrant methylation of tumor suppressor gene (TSG) promoters has been
extensively investigated in nasopharyngeal carcinomas (NPC) from South East Asia but not …

The molecular basis of cancer encompasses both genetic and epigenetic alterations. These
epigenetic changes primarily involve global DNA methylation changes in the form of …

Background and Aims. Vascular smooth muscle cells (VSMCs) are central components of
atherosclerotic plaque. Loss of VSMCs through apoptotic cell death can cause fibrous cap …

Apoptosis is a critical cellular process that balances the effects of cell proliferation and cell
death. MicroRNAs play important roles in cell growth, differentiation, and apoptosis. In this …

Oral Diseases (2011) 17, 794–800 Objectives: Recent studies indicate various molecular
abnormalities in oral squamous cell carcinomas (OSCC), including DNA methylation of …

Promoter methylation reflects in the inactivation of different genes like O6-methylguanine-
DNA methyltransferase DNA repair gene and runt-related transcription factor 3, a known …