In recent years, the demand for novel antifungal therapies has increased several-folds due
to its potential to treat severe biofilm-associated infections. Biofilms are made by the sessile …

Multidrug-resistant (MDR) pathogens pose a well-recognized global health threat that
demands effective solutions; the situation is deemed a global priority by the World Health …

The emergence of new fungal pathogens makes the development of new antifungal drugs a
medical imperative that in recent years motivates the talents of numerous investigators …

Fungal infections impact the lives of at least 12 million people every year, killing over 1.5
million. Wide-spread use of fungicides and prophylactic antifungal therapy have driven …

Cancer is a major public health problem and one of the leading contributors to the global
disease burden. The high cost of development of new drugs and the increasingly severe …

Astrocytes are multifunctional glial cells that play essential roles in supporting synaptic
signalling and white matter-associated connectivity. There is increasing evidence that …

Control of fungal pathogens is increasingly problematic due to the limited number of
effective drugs available for antifungal therapy. Conventional antifungal drugs could also …

The spreading of antibiotic resistance is responsible annually for over 700,000 deaths
worldwide, and the prevision is that this number will increase exponentially. The …

Immunodepression, whether due to HIV infection or organ transplantation, has increased
human vulnerability to fungal infections. These conditions have created an optimal …

Despite the high morbidity and mortality of invasive fungal infections (IFIs), effective and safe
antifungal agents are rather limited. Starting from antifungal lead compound haloperidol that …