DNA methylation is one of the best-characterized epigenetic modifications and has been
implicated in numerous biological processes, including transposable element silencing …

The concept of 'lifestyle 'includes different factors such as nutrition, behavior, stress, physical
activity, working habits, smoking and alcohol consumption. Increasing evidence shows that …

Epigenetic modification refers to heritable changes in gene function that cannot be
explained by alterations in the DNA sequence. The current literature clearly demonstrates …

The aetiology of most neurodegenerative disorders is multifactorial and consists of an
interaction between environmental factors and genetic predisposition. Free radicals derived …

In the present review we summarize recent advances in the understanding of the interaction
between genetics and environmental factors involved in complex multi-factorial …

Epigenetics and epigenomic medicine encompass a new science of brain and behavior that
are already providing unique insights into the mechanisms underlying brain development …

The past few years have seen the identification of dozens of genes with causal roles in
motor neuron diseases (MNDs), particularly for amyotrophic lateral sclerosis and hereditary …

Exposure to airborne particulate matter (PM) has been associated with detrimental health
effects. DNA methylation represents the most well-studied epigenetic factor among the …

Objective: To investigate whether epigenetic mechanisms can regulate leptin's expression
and affect its downstream targets as metalloproteinases 3, 9, 13 in osteoarthritic …

Periodontitis is an infectious, inflammatory disease that is associated with a complex
interplay between specific bacteria, host response, and environmental factors. Because of its …