Increasingly ineffective antibiotics and rapid spread of multi-and pan-resistant bacteria
represent a global health threat; hence, the need of developing new antimicrobial …

This review covers the most recent advances in the development of inhibitors for the
bacterial enzyme sortase A (SrtA). Sortase A (SrtA) is a critical virulence factor, present …

Sortase enzymes are cysteine transpeptidases that attach environmental sensors, toxins,
and other proteins to the cell surface in Gram-positive bacteria. The recognition motif for …

The anti-biofilm and anti-virulence potential of the essential oil (EO) extracted from
Hedychium larsenii M. Dan & Sathish was determined against Streptococcus pyogenes. A …

Sortases are a group of enzymes displayed on the cell‐wall of Gram‐positive bacteria. They
are responsible for the attachment of virulence factors onto the peptidoglycan in a …

Staphylococcus aureus sortase A (SaSrtA) is an enzyme that anchors proteins to the cell
surface of Gram-positive bacteria. During the transpeptidation reaction performed by SaSrtA …

Increasing antimicrobial resistance is a major global health concern. Conventional
antibiotics apply selection pressures, which promote the accumulation of resistant microbes …

Streptococcus pyogenes (group A streptococci; GAS) is an exclusively human pathogen. It
causes a variety of suppurative and non-suppurative diseases in people of all ages …

High school science fairs provide an exceptional opportunity for students to gain experience
with scientific research, and participation has positive outcomes with respect to chosen …

Sortase enzymes are cysteine transpeptidases that attach environmental sensors, toxins,
and other proteins to the cell surface in Gram-positive bacteria. The recognition motif for …