[HTML][HTML] The emergence, genomic diversity and global spread of SARS-CoV-2

J Li, S Lai, GF Gao, W Shi - Nature, 2021 - nature.com
Since the first cases of COVID-19 were documented in Wuhan, China in 2019, the world has
witnessed a devastating global pandemic, with more than 238 million cases, nearly 5 million …

Lessons learned 1 year after SARS-CoV-2 emergence leading to COVID-19 pandemic

KKW To, S Sridhar, KHY Chiu, DLL Hung… - Emerging microbes & …, 2021 - Taylor & Francis
Without modern medical management and vaccines, the severity of the Coronavirus
Disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome (SARS) …

SARS-CoV-2 within-host diversity and transmission

KA Lythgoe, M Hall, L Ferretti, M de Cesare… - Science, 2021 - science.org
INTRODUCTION Genome sequencing at an unprecedented scale during the severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic is helping to track spread of …

The total number and mass of SARS-CoV-2 virions

R Sender, YM Bar-On, S Gleizer… - Proceedings of the …, 2021 - National Acad Sciences
Quantitatively describing the time course of the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infection within an infected individual is important for …

[HTML][HTML] Impaired detection of omicron by SARS-CoV-2 rapid antigen tests

A Osterman, I Badell, E Basara, M Stern… - Medical microbiology …, 2022 - Springer
Since autumn 2020, rapid antigen tests (RATs) have been implemented in several countries
as an important pillar of the national testing strategy to rapidly screen for infections on site …

SARS-CoV-2 mutations in MHC-I-restricted epitopes evade CD8+ T cell responses

B Agerer, M Koblischke, V Gudipati… - Science …, 2021 - science.org
CD8+ T cell immunity to SARS-CoV-2 has been implicated in COVID-19 severity and virus
control. Here, we identified nonsynonymous mutations in MHC-I-restricted CD8+ T cell …

Breathing, speaking, coughing or sneezing: What drives transmission of SARS‐CoV‐2?

V Stadnytskyi, P Anfinrud, A Bax - Journal of Internal Medicine, 2021 - Wiley Online Library
The SARS‐CoV‐2 virus is highly contagious, as demonstrated by numerous well‐
documented superspreading events. The infection commonly starts in the upper respiratory …

[HTML][HTML] Viral variant-resolved wastewater surveillance of SARS-CoV-2 at national scale

F Amman, R Markt, L Endler, S Hupfauf, B Agerer… - Nature …, 2022 - nature.com
SARS-CoV-2 surveillance by wastewater-based epidemiology is poised to provide a
complementary approach to sequencing individual cases. However, robust quantification of …

[HTML][HTML] Accelerated SARS-CoV-2 intrahost evolution leading to distinct genotypes during chronic infection

C Chaguza, AM Hahn, ME Petrone, S Zhou… - Cell Reports …, 2023 - cell.com
The chronic infection hypothesis for novel severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) variant emergence is increasingly gaining credence following the …

[HTML][HTML] Patterns of within-host genetic diversity in SARS-CoV-2

G Tonkin-Hill, I Martincorena, R Amato, ARJ Lawson… - elife, 2021 - elifesciences.org
Monitoring the spread of SARS-CoV-2 and reconstructing transmission chains has become
a major public health focus for many governments around the world. The modest mutation …