COVID-19-associated fungal infections

M Hoenigl, D Seidel, R Sprute, C Cunha… - Nature …, 2022 - nature.com
Abstract Coronavirus disease 2019 (COVID-19)-associated invasive fungal infections are an
important complication in a substantial number of critically ill, hospitalized patients with …

Tackling the emerging threat of antifungal resistance to human health

MC Fisher, A Alastruey-Izquierdo, J Berman… - Nature reviews …, 2022 - nature.com
Invasive fungal infections pose an important threat to public health and are an under-
recognized component of antimicrobial resistance, an emerging crisis worldwide. Across a …

A visual and comprehensive review on COVID-19-associated pulmonary aspergillosis (CAPA)

S Feys, MP Almyroudi, R Braspenning, K Lagrou… - Journal of Fungi, 2021 - mdpi.com
Coronavirus disease 19 (COVID-19)-associated pulmonary aspergillosis (CAPA) is a severe
fungal infection complicating critically ill COVID-19 patients. Numerous retrospective and …

Lung epithelial and myeloid innate immunity in influenza-associated or COVID-19-associated pulmonary aspergillosis: an observational study

S Feys, SM Gonçalves, M Khan, S Choi… - The Lancet …, 2022 - thelancet.com
Background Influenza-associated pulmonary aspergillosis (IAPA) and COVID-19-associated
pulmonary aspergillosis (CAPA) affect about 15% of critically ill patients with influenza or …

A B1a–natural IgG–neutrophil axis is impaired in viral-and steroid-associated aspergillosis

N Sarden, S Sinha, KG Potts, E Pernet… - Science Translational …, 2022 - science.org
The lung naturally resists Aspergillus fumigatus (Af) in healthy individuals, but multiple
conditions can disrupt this resistance, leading to lethal invasive infections. Core processes …

Increased deaths from fungal infections during the coronavirus disease 2019 pandemic—National Vital Statistics System, United States, January 2020–December …

JAW Gold, FB Ahmad, JA Cisewski… - Clinical Infectious …, 2023 - academic.oup.com
Abstract Background Coronavirus disease 2019 (COVID-19)–associated fungal infections
cause severe illness, but comprehensive data on disease burden are lacking. We analyzed …

Invasive pulmonary aspergillosis among intubated patients with SARS-CoV-2 or influenza pneumonia: a European multicenter comparative cohort study

A Rouzé, E Lemaitre, I Martin-Loeches, P Povoa… - Critical Care, 2022 - Springer
Background Recent multicenter studies identified COVID-19 as a risk factor for invasive
pulmonary aspergillosis (IPA). However, no large multicenter study has compared the …

Corticosteroids as risk factor for COVID-19-associated pulmonary aspergillosis in intensive care patients

R Leistner, L Schroeter, T Adam, D Poddubnyy… - Critical Care, 2022 - Springer
Purpose Corticosteroids, in particular dexamethasone, are one of the primary treatment
options for critically ill COVID-19 patients. However, there are a growing number of cases …

High burden of COVID-19-associated pulmonary aspergillosis in severely immunocompromised patients requiring mechanical ventilation

S Feys, K Lagrou, HM Lauwers… - Clinical Infectious …, 2024 - academic.oup.com
Abstract Background Coronavirus disease 2019 (COVID-19)–associated pulmonary
aspergillosis (CAPA) is a frequent superinfection in critically ill patients with COVID-19 and …

Prevalence of COVID-19-associated pulmonary aspergillosis: critical review and conclusions

M Egger, L Bussini, M Hoenigl, M Bartoletti - Journal of Fungi, 2022 - mdpi.com
First reports of cases and case series of COVID-19-associated pulmonary aspergillosis
(CAPA) emerged during the first months of the pandemic. Prevalence rates varied widely …