Depending on their primary structure, the 28 mammalian transient receptor potential (TRP)
cation channels identified so far can be sorted into 6 subfamilies: TRPC (“Canonical”), TRPV …

Transient receptor potential vanilloid 1 (TRPV1) is an ion channel present on sensory
neurons which is activated by heat, protons, capsaicin and a variety of endogenous lipids …

The adequate stimuli and molecular receptors for muscle metaboreceptors and nociceptors
are still under investigation. We used calcium imaging of cultured primary sensory dorsal …

Vanilloid receptor-1 (TRPV1) is a non-selective cation channel, predominantly expressed by
peripheral sensory neurones, which is known to play a key role in the detection of noxious …

Members of the transient receptor potential (TRP) family of nonselective cation channels are
involved in several pathological and physiological conditions. The search for the molecular …

Purpose.: To determine whether hypertonic stress promotes increases in inflammatory
cytokine release through transient receptor potential vanilloid channel type 1 (TRPV1) …

Histamine is known to excite a subset of C-fibers and cause itch sensation. Despite its well-
defined excitatory action on sensory neurons, intracellular signaling mechanisms are not …

The identification and cloning of the vanilloid receptor 1 (TRPV1) represented a significant
step for the understanding of the molecular mechanisms underlying the transduction of …

Isosteric replacement of the phenolic hydroxyl group in potent vanilloid receptor (VR1)
agonists with the alkylsulfonamido group provides a series of compounds which are …

Since the molecular identification of the capsaicin receptor, now known as TRPV1, transient
receptor potential (TRP) channels have occupied an important place in the understanding of …