Redox biology of respiratory viral infections

OA Khomich, SN Kochetkov, B Bartosch, AV Ivanov - Viruses, 2018 - mdpi.com
Respiratory viruses cause infections of the upper or lower respiratory tract and they are
responsible for the common cold—the most prevalent disease in the world. In many cases …

Implications of oxidative stress on viral pathogenesis

FC Camini, CC da Silva Caetano, LT Almeida… - Archives of …, 2017 - Springer
Reactive species are frequently formed after viral infections. Antioxidant defences, including
enzymatic and non-enzymatic components, protect against reactive species, but sometimes …

Extreme heterogeneity of influenza virus infection in single cells

AB Russell, C Trapnell, JD Bloom - Elife, 2018 - elifesciences.org
Viral infection can dramatically alter a cell's transcriptome. However, these changes have
mostly been studied by bulk measurements on many cells. Here we use single-cell mRNA …

Potential molecular mechanisms of zinc-and copper-mediated antiviral activity on COVID-19

I Rani, A Goyal, M Bhatnagar, S Manhas, P Goel, A Pal… - Nutrition Research, 2021 - Elsevier
Abstract Novel coronavirus disease 2019 (COVID-19) has spread across the globe; and
surprisingly, no potentially protective or therapeutic antiviral molecules are available to treat …

[HTML][HTML] The role of oxidative stress in influenza virus infection

M Liu, F Chen, T Liu, F Chen, S Liu, J Yang - Microbes and infection, 2017 - Elsevier
Virus-induced oxidative stress plays an important role in the regulation of the host immune
system. In this review, we provide backgrounds of the pathogenic mechanism of oxidative …

SARS‐CoV‐2 and other respiratory viruses: what does oxidative stress have to do with it?

IG Fernandes, CA de Brito… - Oxidative medicine …, 2020 - Wiley Online Library
The phenomenon of oxidative stress, characterized as an imbalance in the production of
reactive oxygen species and antioxidant responses, is a well‐known inflammatory …

Intranasal delivery of copper oxide nanoparticles induces pulmonary toxicity and fibrosis in C57BL/6 mice

X Lai, H Zhao, Y Zhang, K Guo, Y Xu, S Chen… - Scientific reports, 2018 - nature.com
Abstract Copper oxide nanoparticles (CuO NPs) are widely used as catalysts or
semiconductors in material fields. Recent studies have suggested that CuO NPs have …

Influenza M2 protein regulates MAVS-mediated signaling pathway through interacting with MAVS and increasing ROS production

R Wang, Y Zhu, X Lin, C Ren, J Zhao, F Wang, X Gao… - Autophagy, 2019 - Taylor & Francis
Influenza A virus can evade host innate immune response that is involved in several viral
proteins with complicated mechanisms. To date, how influenza A M2 protein modulates the …

The initiator of neuroexcitotoxicity and ferroptosis in ischemic stroke: glutamate accumulation

G Fan, M Liu, J Liu, Y Huang - Frontiers in Molecular Neuroscience, 2023 - frontiersin.org
Glutamate plays an important role in excitotoxicity and ferroptosis. Excitotoxicity occurs
through over-stimulation of glutamate receptors, specifically NMDAR, while in the non …

Redox control in the pathophysiology of influenza virus infection

KK Chen, M Minakuchi, K Wuputra, CC Ku, JB Pan… - BMC microbiology, 2020 - Springer
Triggered in response to external and internal ligands in cells and animals, redox
homeostasis is transmitted via signal molecules involved in defense redox mechanisms …