Hypo-responsiveness to controlled ovarian stimulation is an undervalued topic in
reproductive medicine. This phenomenon manifests as a low follicles output rate (FORT) …

Background: Human reproduction is regulated by the combined action of the follicle-
stimulating hormone (FSH) and the luteinizing hormone (LH) on the gonads. Although FSH …

BACKGROUND Genotype has been implicated in the outcome of ovarian stimulation. The
analysis of patient-specific genotypes might lead to an individualized pharmacogenomic …

POSEIDON groups 1 and 2 patients respond poorly (< 4 oocytes retrieved) or sub-optimally
(4–9 oocytes retrieved) to gonadotropin stimulation despite the presence of adequate …

Objective To assess the pharmacogenetic potential of FSH for infertility treatment. Design
Review of the literature and genomic databases. Methods Single-nucleotide polymorphism …

FSH brings about its physiological actions by activating a specific receptor located on target
cells. Normal functioning of the FSH receptor (FSHR) is crucial for follicular development …

Background A Delphi consensus was conducted to evaluate the influence of single
nucleotide polymorphisms (SNPs) in genes encoding gonadotropin and gonadotropin …

Objective To study the role of recombinant human LH supplementation in women with hypo-
response to ovarian stimulation. Methods We performed a systematic review and meta …

Context Despite the new opportunities provided by assisted reproductive technology (ART),
male infertility treatment is far from being optimized. One possibility, based on …

Since gonadotropins are the fundamental hormones that control ovarian activity, genetic
polymorphisms may alter gonadal responsiveness to glycoproteins; hence they are …