Understanding ovarian hypo-response to exogenous gonadotropin in ovarian stimulation and its new proposed marker—the follicle-to-oocyte (FOI) index
Hypo-responsiveness to controlled ovarian stimulation is an undervalued topic in
reproductive medicine. This phenomenon manifests as a low follicles output rate (FORT) …
reproductive medicine. This phenomenon manifests as a low follicles output rate (FORT) …
Follicle-stimulating hormone (FSH) action on spermatogenesis: a focus on physiological and therapeutic roles
Background: Human reproduction is regulated by the combined action of the follicle-
stimulating hormone (FSH) and the luteinizing hormone (LH) on the gonads. Although FSH …
stimulating hormone (FSH) and the luteinizing hormone (LH) on the gonads. Although FSH …
Clinical relevance of genetic variants of gonadotrophins and their receptors in controlled ovarian stimulation: a systematic review and meta-analysis
BACKGROUND Genotype has been implicated in the outcome of ovarian stimulation. The
analysis of patient-specific genotypes might lead to an individualized pharmacogenomic …
analysis of patient-specific genotypes might lead to an individualized pharmacogenomic …
Management of women with an unexpected low ovarian response to gonadotropin
A Conforti, SC Esteves, D Cimadomo… - Frontiers in …, 2019 - frontiersin.org
POSEIDON groups 1 and 2 patients respond poorly (< 4 oocytes retrieved) or sub-optimally
(4–9 oocytes retrieved) to gonadotropin stimulation despite the presence of adequate …
(4–9 oocytes retrieved) to gonadotropin stimulation despite the presence of adequate …
Mechanisms in endocrinology: genetics of FSH action: a 2014-and-beyond view
M Simoni, L Casarini - European journal of endocrinology, 2014 - academic.oup.com
Objective To assess the pharmacogenetic potential of FSH for infertility treatment. Design
Review of the literature and genomic databases. Methods Single-nucleotide polymorphism …
Review of the literature and genomic databases. Methods Single-nucleotide polymorphism …
Mutations and polymorphisms in FSH receptor: functional implications in human reproduction
SS Desai, BS Roy, SD Mahale - Reproduction, 2013 - rep.bioscientifica.com
FSH brings about its physiological actions by activating a specific receptor located on target
cells. Normal functioning of the FSH receptor (FSHR) is crucial for follicular development …
cells. Normal functioning of the FSH receptor (FSHR) is crucial for follicular development …
Effect of genetic variants of gonadotropins and their receptors on ovarian stimulation outcomes: a delphi consensus
Background A Delphi consensus was conducted to evaluate the influence of single
nucleotide polymorphisms (SNPs) in genes encoding gonadotropin and gonadotropin …
nucleotide polymorphisms (SNPs) in genes encoding gonadotropin and gonadotropin …
The role of recombinant LH in women with hypo-response to controlled ovarian stimulation: a systematic review and meta-analysis
A Conforti, SC Esteves, F Di Rella, I Strina… - Reproductive Biology …, 2019 - Springer
Objective To study the role of recombinant human LH supplementation in women with hypo-
response to ovarian stimulation. Methods We performed a systematic review and meta …
response to ovarian stimulation. Methods We performed a systematic review and meta …
Prospects for FSH treatment of male infertility
Context Despite the new opportunities provided by assisted reproductive technology (ART),
male infertility treatment is far from being optimized. One possibility, based on …
male infertility treatment is far from being optimized. One possibility, based on …
[HTML][HTML] Polymorphisms in gonadotropin and gonadotropin receptor genes as markers of ovarian reserve and response in in vitro fertilization
A La Marca, G Sighinolfi, C Argento, V Grisendi… - Fertility and sterility, 2013 - Elsevier
Since gonadotropins are the fundamental hormones that control ovarian activity, genetic
polymorphisms may alter gonadal responsiveness to glycoproteins; hence they are …
polymorphisms may alter gonadal responsiveness to glycoproteins; hence they are …