Seronegative spondyloarthropathy (SpA) usually starts in the third decade of life with
negative rheumatoid factor, human leukocyte antigen-B27 genetic marker and clinical …

Chronic recurrent multifocal osteomyelitis (CRMO) is an autoinflammatory disease occurring
mainly in the pediatric age group (before 16 years) and generally presents as a separate …

Multiple studies have shown the microbiota to be abnormal in patients with spondyloarthritis
(SpA). The purpose of this study was to explore the genetic contributions of these microbiota …

The challenges of childhood uveitis lie in the varied spectrum of its clinical presentation, the
often asymptomatic nature of disease, and the evolving nature of the phenotype alongside …

Objective Given the multifactorial pathogenesis of juvenile spondyloarthritis (JSpA) and
evidence of a protective effect in phenotypically similar diseases, we aimed to test whether …

Whole-body magnetic resonance imaging (WBMRI) is an imaging method that provides high
spatial and contrast resolution images without ionizing radiation. 1, 2 Its first clinical …

Background Enthesitis/spondylitis-related arthritis (ERA) is a type of juvenile idiopathic
arthritis (JIA) frequently associated with HLA-B27. In sub-Saharan Africa, HLA-B27-positive …

Objectives Extra-osseous (EO) manifestations are poorly characterized in chronic recurrent
multifocal osteomyelitis (CRMO). This study aimed to further define the frequency …

Autoimmunity is a breakdown of the normal mechanisms that maintain immunologic
homeostasis in the immune system response to specific antigens. The pathogenesis of …

ABSTRACT A 15-year-old girl had experienced hip pain at 11 years of age. At 15 years of
age, the patient complained of persistent generalised pain. Her rheumatoid factor and serum …