Chargé, Sophie BP, and Michael A. Rudnicki. Cellular and Molecular Regulation of Muscle
Regeneration. Physiol Rev 84: 209–238, 2004; 10.1152/physrev. 00019.2003.—Under …

Satellite cells are dormant progenitors located at the periphery of skeletal myofibers that can
be triggered to proliferate for both self-renewal and differentiation into myogenic cells. In …

The plasminogen system is a critical proteolytic system responsible for the remodeling of the
extracellular matrix (ECM). The master regulator of the plasminogen system, plasminogen …

Muscle recently has been identified as a good source of adult stem cells that can
differentiate into cells of different lineages. The most well-known muscle progenitor cells are …

Transplantation of muscle precursor cells is of therapeutic interest for focal skeletal muscular
diseases. However, major limitations of cell transplantation are the poor survival, expansion …

Background. Hyperacute rejection of vascularized discordant xenografts can now be
effectively managed. However, acute vascular rejection (AVR) then ensues, resulting in graft …

The implantation of cultured myogenic cells into the body (myoblast transplantation) is an
experimental strategy that is being explored for the potential treatment of myopathies. Its …

Duchenne muscular dystrophy is a devastating muscular dystrophy of childhood. Mutations
in the dystrophin gene destroy the link between the internal muscle filaments and the …

Different molecules are available to recruit new neighboring myogenic cells to the site of
regeneration. Formerly called B cell stimulatory factor-1, IL-4 can now be included in the list …

Duchenne muscular dystrophy (DMD) is a fatal and incurable muscle degenerative disorder.
We identify a function of the protease urokinase plasminogen activator (uPA) in mdx mice, a …