Complicated role of post-translational modification and protease-cleaved fragments of tau in Alzheimer's Disease and other tauopathies

J Yang, N Shen, J Shen, Y Yang, HL Li - Molecular Neurobiology, 2024 - Springer
Tau, a microtubule-associated protein predominantly localized in neuronal axons, plays a
crucial role in promoting microtubule assembly, stabilizing their structure, and participating …

Pathological impact of tau proteolytical process on neuronal and mitochondrial function: a crucial role in alzheimer's disease

MA Olesen, RA Quintanilla - Molecular Neurobiology, 2023 - Springer
Tau protein plays a pivotal role in the central nervous system (CNS), participating in
microtubule stability, axonal transport, and synaptic communication. Research interest has …

Syntaphilin inactivation can enhance axonal mitochondrial transport to improve spinal cord injury

Q Lu, Y Zhang, BOA Botchway, M Huang, X Liu - Molecular Neurobiology, 2023 - Springer
Mitochondria are important organelle of eukaryotic cells. They consists of a large number of
different proteins that provide most of the ATP and supply power for the growth, function, and …

Effect of tau protein on mitochondrial functions

KK Epremyan, TN Goleva, RA Zvyagilskaya - Biochemistry (Moscow), 2022 - Springer
Alzheimer's disease is the most common age-related progressive neurodegenerative
disorder of brain cortex and hippocampus leading to cognitive impairment. Accumulation of …

[HTML][HTML] Molecular mechanisms of neurodegenerative disease (NDD)

A Chakraborty, A Diwan - AIMS Molecular Science, 2023 - aimspress.com
Degenerative nerve diseases affect body's balance, movement, speech, breathing and heart
function. Classification of neurodegenerative disorders can be done on the basis of their …