Autologous activated platelet-rich plasma injection into adult human ovary tissue: molecular mechanism, analysis, and discussion of reproductive response
ES Sills, SH Wood - Bioscience Reports, 2019 - portlandpress.com
In clinical infertility practice, one intractable problem is low (or absent) ovarian reserve which
in turn reflects the natural oocyte depletion associated with advancing maternal age. The …
in turn reflects the natural oocyte depletion associated with advancing maternal age. The …
Autologous germline mitochondrial energy transfer (AUGMENT) in human assisted reproduction
Ovarian aging is characterized by a decline in both the total number and overall quality of
oocytes, the latter of which has been experimentally tied to mitochondrial dysfunction …
oocytes, the latter of which has been experimentally tied to mitochondrial dysfunction …
In vitro differentiation of human oocyte-like cells from oogonial stem cells: single-cell isolation and molecular characterization
E Silvestris, P Cafforio, S D'oronzo, C Felici… - Human …, 2018 - academic.oup.com
STUDY QUESTION Are the large cells derived from cultured DEAD box polypeptide 4
(DDX4)-positive oogonial stem cells (OSCs), isolated from the ovarian cortex of non …
(DDX4)-positive oogonial stem cells (OSCs), isolated from the ovarian cortex of non …
[HTML][HTML] Implications and current limitations of oogenesis from female germline or oogonial stem cells in adult mammalian ovaries
A now large body of evidence supports the existence of mitotically active germ cells in
postnatal ovaries of diverse mammalian species, including humans. This opens the …
postnatal ovaries of diverse mammalian species, including humans. This opens the …
Stem cells, progenitor cells, and lineage decisions in the ovary
Exploring stem cells in the mammalian ovary has unleashed a Pandora's box of new
insights and questions. Recent evidence supports the existence of stem cells of a number of …
insights and questions. Recent evidence supports the existence of stem cells of a number of …
[HTML][HTML] Human GV oocytes generated by mitotically active germ cells obtained from follicular aspirates
X Ding, G Liu, B Xu, C Wu, N Hui, X Ni, J Wang, M Du… - Scientific reports, 2016 - nature.com
Human female germline stem cells (FGSCs) have opened new opportunities for
understanding human oogenesis, delaying menopause, treating infertility and providing a …
understanding human oogenesis, delaying menopause, treating infertility and providing a …
[HTML][HTML] From primordial germ cells to primordial follicles: a review and visual representation of early ovarian development in mice
HM Wear, MJ McPike, KH Watanabe - Journal of ovarian research, 2016 - Springer
Background Normal development of reproductive organs is crucial for successful
reproduction. In mice the early ovarian developmental process occurs during the embryonic …
reproduction. In mice the early ovarian developmental process occurs during the embryonic …
[HTML][HTML] Recent progress towards understanding the role of DNA methylation in human placental development
Epigenetic modifications, and particularly DNA methylation, have been studied in many
tissues, both healthy and diseased, and across numerous developmental stages. The …
tissues, both healthy and diseased, and across numerous developmental stages. The …
Ovarian regeneration: the potential for stem cell contribution in the postnatal ovary to sustained endocrine function
The endocrine function of the ovary is dependent upon the ovarian follicle, which on a
cellular basis consists of an oocyte surrounded by adjacent somatic cells responsible for …
cellular basis consists of an oocyte surrounded by adjacent somatic cells responsible for …
In vitro cytotoxicity of zinc oxide nanoparticles in mouse ovarian germ cells
M Saber, RS Hayaei-Tehrani, S Mokhtari, P Hoorzad… - Toxicology in Vitro, 2021 - Elsevier
Recently, metal oxide nanoparticles such as zinc oxide nanoparticles (ZnO-NPs) have
received considerable attention and humans are exposed to them in everyday life. The …
received considerable attention and humans are exposed to them in everyday life. The …