Control of RNA stability in immunity
S Akira, K Maeda - Annual review of immunology, 2021 - annualreviews.org
Posttranscriptional control of mRNA regulates various biological processes, including
inflammatory and immune responses. RNA-binding proteins (RBPs) bind cis-regulatory …
inflammatory and immune responses. RNA-binding proteins (RBPs) bind cis-regulatory …
Focus on the role of the NLRP3 inflammasome in multiple sclerosis: pathogenesis, diagnosis, and therapeutics
Y Cui, H Yu, Z Bu, L Wen, L Yan, J Feng - Frontiers in Molecular …, 2022 - frontiersin.org
Neuroinflammation is initiated with an aberrant innate immune response in the central
nervous system (CNS) and is involved in many neurological diseases. Inflammasomes are …
nervous system (CNS) and is involved in many neurological diseases. Inflammasomes are …
CRISPRi screens in human iPSC-derived astrocytes elucidate regulators of distinct inflammatory reactive states
Astrocytes become reactive in response to insults to the central nervous system by adopting
context-specific cellular signatures and outputs, but a systematic understanding of the …
context-specific cellular signatures and outputs, but a systematic understanding of the …
Anti-inflammatory effects of minor cannabinoids CBC, THCV, and CBN in human macrophages
Inflammation is a natural response of the body to signals of tissue damage or infection
caused by pathogens. However, when it becomes imbalanced, it can lead to various …
caused by pathogens. However, when it becomes imbalanced, it can lead to various …
Induction of unique macrophage subset by simultaneous stimulation with LPS and IL-4
K Ishida, T Nagatake, A Saika, S Kawai… - Frontiers in …, 2023 - frontiersin.org
Macrophages manifest as various subtypes that play diverse and important roles in
immunosurveillance and the maintenance of immunological homeostasis in various tissues …
immunosurveillance and the maintenance of immunological homeostasis in various tissues …
Roles of RNA-binding proteins in immune diseases and cancer
S Hashimoto, T Kishimoto - Seminars in cancer biology, 2022 - Elsevier
Genetic information that is transcribed from DNA to mRNA, and then translated from mRNA
to protein, is regulated by complex and sophisticated post-transcriptional mechanisms …
to protein, is regulated by complex and sophisticated post-transcriptional mechanisms …
[HTML][HTML] Monocyte-released HERV-K dUTPase engages TLR4 and MCAM causing endothelial mesenchymal transition
We previously reported heightened expression of the human endogenous retroviral protein
HERV-K deoxyuridine triphosphate nucleotidohydrolase (dUTPase) in circulating …
HERV-K deoxyuridine triphosphate nucleotidohydrolase (dUTPase) in circulating …
Helicobacter pylori Infection of Primary Human Monocytes Boosts Subsequent Immune Responses to LPS
T Frauenlob, T Neuper, M Mehinagic… - Frontiers in …, 2022 - frontiersin.org
Infection with Helicobacter pylori (H. pylori) affects almost half of the world's population and
is a major cause of stomach cancer. Although immune cells react strongly to this gastric …
is a major cause of stomach cancer. Although immune cells react strongly to this gastric …
3ʹ, 4ʹ-Dihydroxyflavone mitigates inflammatory responses by inhibiting LPS and TLR4/MD2 interaction
HH Lee, JS Shin, KS Chung, JM Kim, SH Jung, HS Yoo… - Phytomedicine, 2023 - Elsevier
Background We previously reported the potential inhibitory activity of 3ʹ, 4ʹ-
dihydroxyflavone (DHF) on nitric oxide (NO) and prostaglandin E 2 (PGE 2) production in …
dihydroxyflavone (DHF) on nitric oxide (NO) and prostaglandin E 2 (PGE 2) production in …
Brain-gut-liver axis: Chronic psychological stress promotes liver injury and fibrosis via gut in rats
MY Xu, CC Guo, MY Li, YH Lou, ZR Chen… - Frontiers in Cellular …, 2022 - frontiersin.org
Background The effect of chronic psychological stress on hepatitis and liver fibrosis is
concerned. However, its mechanism remains unclear. We investigated the effect and …
concerned. However, its mechanism remains unclear. We investigated the effect and …