[HTML][HTML] Head and neck squamous cell carcinoma

DE Johnson, B Burtness, CR Leemans… - Nature reviews Disease …, 2020 - nature.com
Most head and neck cancers are derived from the mucosal epithelium in the oral cavity,
pharynx and larynx and are known collectively as head and neck squamous cell carcinoma …

[HTML][HTML] Epidemiology, risk factors, and prevention of head and neck squamous cell carcinoma

A Barsouk, JS Aluru, P Rawla, K Saginala, A Barsouk - Medical Sciences, 2023 - mdpi.com
Head and neck squamous cell carcinoma (HNSCC) is a group of malignancies, involving
the oral cavity, pharynx, hypopharynx, larynx, nasal cavity, and salivary glands, that together …

NCCN Guidelines® insights: Head and neck cancers, version 1.2022: Featured updates to the NCCN guidelines

JJ Caudell, ML Gillison, E Maghami, S Spencer… - Journal of the National …, 2022 - jnccn.org
The NCCN Guidelines for Head and Neck Cancers address tumors arising in the oral cavity
(including mucosal lip), pharynx, larynx, and paranasal sinuses. Occult primary cancer …

[HTML][HTML] Phase II randomized trial of transoral surgery and low-dose intensity modulated radiation therapy in resectable p16+ locally advanced oropharynx cancer: an …

RL Ferris, Y Flamand, GS Weinstein, S Li… - Journal of clinical …, 2022 - ncbi.nlm.nih.gov
PURPOSE Definitive or postoperative chemoradiation (CRT) is curative for human
papillomavirus–associated (HPV+) oropharynx cancer (OPC) but induces significant toxicity …

[HTML][HTML] Reduced-dose radiation therapy for HPV-associated oropharyngeal carcinoma (NRG Oncology HN002)

SS Yom, P Torres-Saavedra, JJ Caudell… - Journal of Clinical …, 2021 - ncbi.nlm.nih.gov
PURPOSE Reducing radiation treatment dose could improve the quality of life (QOL) of
patients with good-risk human papillomavirus–associated oropharyngeal squamous cell …

[HTML][HTML] B cell signatures and tertiary lymphoid structures contribute to outcome in head and neck squamous cell carcinoma

AT Ruffin, AR Cillo, T Tabib, A Liu, S Onkar… - Nature …, 2021 - nature.com
Current immunotherapy paradigms aim to reinvigorate CD8+ T cells, but the contribution of
humoral immunity to antitumor immunity remains understudied. Here, we demonstrate that in …

[HTML][HTML] The Society for Immunotherapy of Cancer consensus statement on immunotherapy for the treatment of squamous cell carcinoma of the head and neck …

EEW Cohen, RB Bell, CB Bifulco, B Burtness… - … for immunotherapy of …, 2019 - Springer
Head and neck cancers, including those of the lip and oral cavity, nasal cavity, paranasal
sinuses, oropharynx, larynx and nasopharynx represent nearly 700,000 new cases and …

[HTML][HTML] Safety and efficacy of nivolumab monotherapy in recurrent or metastatic cervical, vaginal, or vulvar carcinoma: results from the phase I/II CheckMate 358 trial

RW Naumann, A Hollebecque, T Meyer… - Journal of Clinical …, 2019 - ncbi.nlm.nih.gov
Safety and Efficacy of Nivolumab Monotherapy in Recurrent or Metastatic Cervical, Vaginal,
or Vulvar Carcinoma: Results From the Phase I/II CheckMate 358 Trial - PMC Back to Top …

Carcinogenic human papillomavirus infection

M Schiffman, J Doorbar, N Wentzensen… - Nature reviews Disease …, 2016 - nature.com
Infections with human papillomavirus (HPV) are common and transmitted by direct contact.
Although the great majority of infections resolve within 2 years, 13 phylogenetically related …

Human papillomavirus testing in head and neck carcinomas: guideline from the College of American Pathologists

JS Lewis Jr, B Beadle, JA Bishop… - … of pathology & …, 2018 - meridian.allenpress.com
Context Human papillomavirus (HPV) is a major cause of oropharyngeal squamous cell
carcinomas, and HPV (and/or surrogate marker p16) status has emerged as a prognostic …