[HTML][HTML] The role of m6A, m5C and Ψ RNA modifications in cancer: Novel therapeutic opportunities
RNA modifications have recently emerged as critical posttranscriptional regulators of gene
expression programmes. Significant advances have been made in understanding the …
expression programmes. Significant advances have been made in understanding the …
[HTML][HTML] Eukaryotic 5-methylcytosine (m5C) RNA Methyltransferases: Mechanisms, Cellular Functions, and Links to Disease
KE Bohnsack, C Höbartner, MT Bohnsack - Genes, 2019 - mdpi.com
5-methylcytosine (m5C) is an abundant RNA modification that's presence is reported in a
wide variety of RNA species, including cytoplasmic and mitochondrial ribosomal RNAs …
wide variety of RNA species, including cytoplasmic and mitochondrial ribosomal RNAs …
5-methylcytosine promotes pathogenesis of bladder cancer through stabilizing mRNAs
X Chen, A Li, BF Sun, Y Yang, YN Han, X Yuan… - Nature cell …, 2019 - nature.com
Abstract Although 5-methylcytosine (m5C) is a widespread modification in RNAs, its
regulation and biological role in pathological conditions (such as cancer) remain unknown …
regulation and biological role in pathological conditions (such as cancer) remain unknown …
[PDF][PDF] Transcriptome-wide mapping of internal N7-methylguanosine methylome in mammalian mRNA
Summary N 7-methylguanosine (m 7 G) is a positively charged, essential modification at the
5′ cap of eukaryotic mRNA, regulating mRNA export, translation, and splicing. m 7 G also …
5′ cap of eukaryotic mRNA, regulating mRNA export, translation, and splicing. m 7 G also …
[HTML][HTML] 5-methylcytosine promotes mRNA export—NSUN2 as the methyltransferase and ALYREF as an m5C reader
methylcytosine (m 5 C) is a post-transcriptional RNA modification identified in both stable
and highly abundant tRNAs and rRNAs, and in mRNAs. However, its regulatory role in …
and highly abundant tRNAs and rRNAs, and in mRNAs. However, its regulatory role in …
N6‐Methyladenosine mRNA methylation is important for salt stress tolerance in Arabidopsis
J Hu, J Cai, SJ Park, K Lee, Y Li, Y Chen… - The Plant …, 2021 - Wiley Online Library
As the most abundant internal modification of mRNA, N6‐methyladenosine (m6A)
methylation of RNA is emerging as a new layer of epitranscriptomic gene regulation in …
methylation of RNA is emerging as a new layer of epitranscriptomic gene regulation in …
[HTML][HTML] Biological roles of RNA m5C modification and its implications in Cancer immunotherapy
H Song, J Zhang, B Liu, J Xu, B Cai, H Yang… - Biomarker …, 2022 - Springer
Epigenetics including DNA and RNA modifications have always been the hotspot field of life
sciences in the post-genome era. Since the first mapping of N6-methyladenosine (m6A) and …
sciences in the post-genome era. Since the first mapping of N6-methyladenosine (m6A) and …
FMRP promotes transcription-coupled homologous recombination via facilitating TET1-mediated m5C RNA modification demethylation
RNA modifications regulate a variety of cellular processes including DNA repair. The RNA
methyltransferase TRDMT1 generates methyl-5-cytosine (m5C) on messenger RNA (mRNA) …
methyltransferase TRDMT1 generates methyl-5-cytosine (m5C) on messenger RNA (mRNA) …
Dynamic transcriptomic m5C and its regulatory role in RNA processing
YS Chen, WL Yang, YL Zhao… - Wiley Interdisciplinary …, 2021 - Wiley Online Library
Abstract RNA 5‐methylcytosine (m5C) is a prevalent RNA modification in multiple RNA
species, including messenger RNAs (mRNAs), transfer RNAs (tRNAs), ribosomal RNAs …
species, including messenger RNAs (mRNAs), transfer RNAs (tRNAs), ribosomal RNAs …
iLearn: an integrated platform and meta-learner for feature engineering, machine-learning analysis and modeling of DNA, RNA and protein sequence data
Z Chen, P Zhao, F Li, TT Marquez-Lago… - Briefings in …, 2020 - academic.oup.com
With the explosive growth of biological sequences generated in the post-genomic era, one
of the most challenging problems in bioinformatics and computational biology is to …
of the most challenging problems in bioinformatics and computational biology is to …