Molecular determinants of BK channel functional diversity and functioning

R Latorre, K Castillo… - Physiological …, 2017 - journals.physiology.org
Large-conductance Ca2+-and voltage-activated K+ (BK) channels play many physiological
roles ranging from the maintenance of smooth muscle tone to hearing and neurosecretion …

BK channels in the central nervous system

C Contet, SP Goulding, DA Kuljis, AL Barth - International review of …, 2016 - Elsevier
Large conductance Ca 2+-and voltage-activated K+(BK) channels are widely distributed in
the postnatal central nervous system (CNS). BK channels play a pleiotropic role in …

The large-conductance, calcium-activated potassium channel: a big key regulator of cell physiology

M Sancho, BD Kyle - Frontiers in Physiology, 2021 - frontiersin.org
Large-conductance Ca2+-activated K+ channels facilitate the efflux of K+ ions from a variety
of cells and tissues following channel activation. It is now recognized that BK channels …

A BK (Slo1) channel journey from molecule to physiology

GF Contreras, K Castillo, N Enrique… - Channels, 2013 - Taylor & Francis
Calcium and voltage-activated potassium (BK) channels are key actors in cell physiology,
both in neuronal and non-neuronal cells and tissues. Through negative feedback between …

MaxiK channel partners: physiological impact

R Lu, A Alioua, Y Kumar, M Eghbali… - The Journal of …, 2006 - Wiley Online Library
The basic functional unit of the large‐conductance, voltage‐and Ca2+‐activated K+ (MaxiK,
BK, BKCa) channel is a tetramer of the pore‐forming α‐subunit (MaxiKα) encoded by a …

The potassium channel odyssey: mechanisms of traffic and membrane arrangement

J Capera, C Serrano-Novillo, M Navarro-Pérez… - International journal of …, 2019 - mdpi.com
Ion channels are transmembrane proteins that conduct specific ions across biological
membranes. Ion channels are present at the onset of many cellular processes, and their …

Intracellular BKCa (iBKCa) channels

H Singh, E Stefani, L Toro - The Journal of physiology, 2012 - Wiley Online Library
The large conductance calcium‐and voltage‐activated potassium channel (BKCa) is widely
expressed at the plasma membrane. This channel is involved in a variety of fundamental …

Functionally Diverse Complement of Large Conductance Calcium-and Voltage-activated Potassium Channel (BK) α-Subunits Generated from a Single Site of Splicing …

L Chen, L Tian, SHF MacDonald, H McClafferty… - Journal of Biological …, 2005 - ASBMB
The pore-forming α-subunits of large conductance calcium-and voltage-activated potassium
(BK) channels are encoded by a single gene that undergoes extensive alternative pre …

Mitochondrial BKCa channel

E Balderas, J Zhang, E Stefani, L Toro - Frontiers in physiology, 2015 - frontiersin.org
Since its discovery in a glioma cell line 15 years ago, mitochondrial BKCa channel
(mitoBKCa) has been studied in brain cells and cardiomyocytes sharing general biophysical …

MaxiK channel and cell signalling

L Toro, M Li, Z Zhang, H Singh, Y Wu… - Pflügers Archiv-European …, 2014 - Springer
Abstract The large-conductance Ca 2+-and voltage-activated K+(MaxiK, BK, BK Ca, Slo1, K
Ca 1.1) channel role in cell signalling is becoming apparent as we learn how the channel …