The two major interfaces separating brain and blood have different primary roles. The
choroid plexuses secrete cerebrospinal fluid into the ventricles, accounting for most net fluid …

Ischaemic stroke results from acute arterial occlusion leading to focal hypoperfusion.
Thrombolysis is the only proven treatment. Advanced neuroimaging techniques allow a …

High-speed high-resolution imaging of the whole-brain hemodynamics is critically important
to facilitating neurovascular research. High imaging speed and image quality are crucial to …

Key points• The partial pressures of arterial carbon dioxide () and oxygen () has a marked
influence on brain blood flow.• It is unclear if the larger brain arteries are also sensitive to …

There is considerable utility in the use of transcranial Doppler ultrasound (TCD) to assess
cerebrovascular function. The brain is unique in its high energy and oxygen demand but …

This review highlights the influence of oxygen (O2) availability on cerebral blood flow (CBF).
Evidence for reductions in O2 content (CaO2) rather than arterial O2 tension (PaO2) as the …

Non‐technical summary Two mechanisms control brain blood flow by changing blood
vessel diameter: autoregulation maintains flow in the face of perfusion pressure changes …

Many sport competitions, typically involving the completion of single-(eg track-and-field or
track cycling events) and multiple-sprint exercises (eg team and racquet sports, cycling …

Key points• Arterial CO2 serves as a mediator of cerebral blood flow, and its relative
influence on the regulation of cerebral blood flow is defined as cerebral CO2 reactivity.• …

Petrassi FA, Hodkinson PD, Walters PL, Gaydos SJ. Hypoxic hypoxia at moderate altitudes:
review of the state of the science. Aviat Space Environ Med 2012; 83: 975–84 …