Normal haemostasis depends on an intricate balance between mechanisms of bleeding and
mechanisms of thrombosis, and this balance can be altered after traumatic brain injury (TBI) …

Rotational thromboelastometry (ROTEM) is a point-of-care viscoelastic method and enables
to assess viscoelastic profiles of whole blood in various clinical settings. ROTEM-guided …

Background Severe traumatic injury continues to present challenges to healthcare systems
around the world, and post-traumatic bleeding remains a leading cause of potentially …

Background Severe trauma represents a major global public health burden and the
management of post-traumatic bleeding continues to challenge healthcare systems around …

Objective: Developing pragmatic data-driven algorithms for management of trauma induced
coagulopathy (TIC) during trauma hemorrhage for viscoelastic hemostatic assays (VHAs) …

The publication of the Clinical Randomization of an Antifibrinolytic in Significant
Hemorrhage-2 (CRASH-2) study and its intense dissemination prompted a renaissance for …

Since the publication of the 2008 Western Trauma Association algorithm for the
management of pelvic fracture with hemodynamic instability, 1 the approach in general has …

POC SCTs are not able to characterise the complexity of trauma-associated coagulopathy.
VETs provide a rapid estimation of underlying haemostatic disorders, thereby providing …

Viscoelastic assays (VEAs) that include thromboelastography and rotational
thromboelastometry add value to the investigation of coagulopathies and goal-directed …

Hellmut Hartert was the first person to exploit the viscoelastic properties of clotting blood to
measure blood coagulation in 1948. Since then, the technology has improved, allowing …