Burn-induced coagulopathies: a comprehensive review

RL Ball, JW Keyloun, K Brummel-Ziedins, T Orfeo… - Shock, 2020 - journals.lww.com
Burn-induced coagulopathy is not well understood, and consensus on diagnosis,
prevention, and treatments are lacking. In this review, literature on burn-induced (and …

[HTML][HTML] Prothrombin complex concentrate for trauma induced coagulopathy: a systematic review and meta-analysis

TW Kao, YC Lee, HT Chang - Journal of acute medicine, 2021 - ncbi.nlm.nih.gov
Background Optimal management for trauma-induced coagulopathy (TIC) is a clinical
conundrum. In conjunction with the transfusion of fresh-frozen plasma (FFP), additional …

Four-factor prothrombin complex concentrate is associated with improved survival in trauma-related hemorrhage: a nationwide propensity-matched analysis

M Zeeshan, M Hamidi, AJ Feinstein… - Journal of Trauma …, 2019 - journals.lww.com
METHODS Two-year (2015–2016) analysis of the American College of Surgeons-Trauma
Quality Improvement Program database. All adult (age≥ 18 years) trauma patients who …

[HTML][HTML] Prothrombin complex concentrate (PCC) for treatment of trauma-induced coagulopathy: systematic review and meta-analyses

I Hannadjas, A James, R Davenport, C Lindsay… - Critical Care, 2023 - Springer
Background Trauma-induced coagulopathy (TIC) is common in trauma patients with major
hemorrhage. Prothrombin complex concentrate (PCC) is used as a potential treatment for …

Hemostatic defects in massive transfusion: an update and treatment recommendations

LM Napolitano - Expert Review of Hematology, 2021 - Taylor & Francis
Introduction Acute hemorrhage is a global healthcare issue, and remains the leading
preventable cause of death in trauma. Acute severe hemorrhage can be related to traumatic …

[HTML][HTML] Prothrombin complex concentrates to treat coagulation disturbances: an overview with a focus on use in infants and children

DM Munlemvo, JD Tobias, KM Chenault… - Cardiology …, 2022 - ncbi.nlm.nih.gov
Various factors may lead to coagulation disturbances following cardiopulmonary bypass and
surgery for congenital heart disease. In addition to the risks associated with the …

Pro–Con Debate: Viscoelastic Hemostatic Assays Should Replace Fixed Ratio Massive Transfusion Protocols in Trauma

KP Blaine, R Dudaryk - Anesthesia & Analgesia, 2022 - journals.lww.com
Major trauma patients at risk of traumatic coagulopathy are commonly treated with early
clotting factor replacement to maintain hemostasis and prevent microvascular bleeding. In …

Four-factor prothrombin complex concentrate in adjunct to whole blood in trauma-related hemorrhage: Does whole blood replace the need for factors?

M Khurrum, M Ditillo, O Obaid, T Anand… - Journal of Trauma …, 2021 - journals.lww.com
BACKGROUND The use of whole blood (WB) for the treatment of hemorrhagic shock and
coagulopathy is increasing in civilian trauma patients. Four-factor prothrombin complex …

[HTML][HTML] Comparison of 3-factor versus 4-factor prothrombin complex concentrate for emergent warfarin reversal: a systematic review and meta-analysis

DJ Margraf, SJ Brown, HL Blue, TL Bezdicek… - BMC emergency …, 2022 - Springer
Background Patients requiring emergent warfarin reversal (EWR) have been prescribed
three-factor prothrombin complex concentrate (PCC3) and four-factor prothrombin complex …

The use of new procoagulants in blunt and penetrating trauma

MR Peralta, P Chowdary - Current Opinion in Anesthesiology, 2019 - journals.lww.com
The use of new procoagulants in blunt and penetrating trauma : Current Opinion in
Anesthesiology The use of new procoagulants in blunt and penetrating trauma : Current …