Life and death of circulating cell-free DNA
A Kustanovich, R Schwartz, T Peretz… - Cancer biology & …, 2019 - Taylor & Francis
Tumor-specific, circulating cell-free DNA in liquid biopsies is a promising source of
biomarkers for minimally invasive serial monitoring of treatment responses in cancer …
biomarkers for minimally invasive serial monitoring of treatment responses in cancer …
Liquid Biopsy Based on Cell-Free DNA and RNA
C Loy, L Ahmann, I De Vlaminck… - Annual Review of …, 2024 - annualreviews.org
This review delves into the rapidly evolving landscape of liquid biopsy technologies based
on cell-free DNA (cfDNA) and cell-free RNA (cfRNA) and their increasingly prominent role in …
on cell-free DNA (cfDNA) and cell-free RNA (cfRNA) and their increasingly prominent role in …
[HTML][HTML] Liquid biopsy for infectious diseases: a focus on microbial cell-free DNA sequencing
D Han, R Li, J Shi, P Tan, R Zhang, J Li - Theranostics, 2020 - ncbi.nlm.nih.gov
Metagenomic next-generation sequencing (mNGS) of microbial cell-free DNA (mcfDNA
sequencing) is becoming an attractive diagnostic modality for infectious diseases, allowing …
sequencing) is becoming an attractive diagnostic modality for infectious diseases, allowing …
Analysis of recurrently protected genomic regions in cell-free DNA found in urine
H Markus, J Zhao, T Contente-Cuomo… - Science translational …, 2021 - science.org
Cell-free DNA (cfDNA) in urine is a promising analyte for noninvasive diagnostics. However,
urine cfDNA is highly fragmented. Whether characteristics of these fragments reflect …
urine cfDNA is highly fragmented. Whether characteristics of these fragments reflect …
Genome-wide analysis of aberrant position and sequence of plasma DNA fragment ends in patients with cancer
Genome-wide fragmentation patterns in cell-free DNA (cfDNA) in plasma are strongly
influenced by cellular origin due to variation in chromatin accessibility across cell types …
influenced by cellular origin due to variation in chromatin accessibility across cell types …
ctDNA predicts overall survival in patients with NSCLC treated with PD-L1 blockade or with chemotherapy
PURPOSE Identification of predictors for overall survival (OS) allows timely detection of
clinical efficacy signals and therefore facilitates treatment decisions. We assessed the …
clinical efficacy signals and therefore facilitates treatment decisions. We assessed the …
A practical guide to chimerism analysis: review of the literature and testing practices worldwide
AG Blouin, F Ye, J Williams, M Askar - Human immunology, 2021 - Elsevier
Abstract Background and Purpose Currently there are no widely accepted guidelines for
chimerism analysis testing in hematopoietic cell transplantation (HCT) patients. The …
chimerism analysis testing in hematopoietic cell transplantation (HCT) patients. The …
Cell-free DNA tissues of origin by methylation profiling reveals significant cell, tissue, and organ-specific injury related to COVID-19 severity
Summary Background Coronavirus disease 2019 (COVID-19) primarily affects the lungs, but
evidence of systemic disease with multi-organ involvement is emerging. Here, we …
evidence of systemic disease with multi-organ involvement is emerging. Here, we …
Methods for non-invasive prenatal ploidy calling
M Rabinowitz, G Gemelos, M Banjevic, A Ryan… - US Patent …, 2022 - Google Patents
The present disclosure provides methods for determining the ploidy status of a chromosome
in a gestating fetus from genotypic data measured from a mixed sample of DNA comprising …
in a gestating fetus from genotypic data measured from a mixed sample of DNA comprising …
Metagenomics to assist in the diagnosis of bloodstream infection
AL Greninger, SN Naccache - The journal of applied laboratory …, 2019 - academic.oup.com
Background Metagenomic next-generation sequencing (mNGS) has emerged as a
promising technology that enables pan-pathogen detection from any source. However …
promising technology that enables pan-pathogen detection from any source. However …